The increasing human settlements around protected areas is a significant cause of the shrinking size of conservation areas globally. This is an alarming situation, especially in countries where protected areas significantly contribute to the National economy. The use of new tools to solve Land use conflicts that exist around protected areas is needed. This study employed the weighted overlay analysis using ecological, social and economic factors to model suitability for developing settlements in Chobe District, an international tourist destination in Northern Botswana, using ArcGIS spatial analyst. The majority of the land (83.4%) in Chobe is not suitable for settlement, while suitable areas that could for settlement remain relatively small (0.3% of the land). This study suggests that more land for settling the increasing population be created out of Chobe District to avoid encroachment on the conservation areas. The study demonstrated that ArcGIS spatial analyst model builder could be integrated into the land resource planning process of protected areas, making it a handy tool for the analysis and the identification of ecological, economic and social factors, thus establishing an excellent area for further research, especially for sustainable management of protected areas.