Self-sampling is more acceptable than the Pap test and could improve coverage rates of early detection programs. The incorporation of self-collected samples to detect HPV could encourage participation in screening programs among those women who reject the Pap test because of the necessary pelvic examination.

Background: Some developer activity traditionally performed manually, such as making code commits, opening, managing, or closing issues is increasingly subject to automation in many OSS projects. Specifically, such activity is often performed by tools that react to events or run at specific times. We refer to such automation tools as bots and, in many software mining scenarios related to developer productivity or code quality, it is desirable to identify bots in order to separate their actions from actions of individuals. Aim: Find an automated way of identifying bots and code committed by these bots, and to characterize the types of bots based on their activity patterns. Method and Result: We propose BIMAN, a systematic approach to detect bots using author names, commit messages, files modified by the commit, and projects associated with the commits. For our test data, the value for AUC-ROC was 0.9. We also characterized these bots based on the time patterns of their code commits and the types of files modified, and found that they primarily work with documentation files and web pages, and these files are most prevalent in HTML and JavaScript ecosystems. We have compiled a shareable dataset containing detailed information about 461 bots we found (all of which have more than 1000 commits) and 13,762,430 commits they created.

Our study showed that, despite obvious anatomical differences, HPV coinfections do seem to occur at random in the male external genitalia as in the female cervix.

Objectives Genital HPV infection in men causes benign and cancerous lesions, the incidence of which differs by age. The goal of this work was to comprehensively evaluate incidence and clearance of individual HPV genotypes among men by age group. Methods HIV-negative men ages 18–70 with no history of anogenital cancer were recruited for the HPV Infection in Men (HIM) Study. Participants completed clinical exams and questionnaires every six months for up to ~4 years. Genital specimens underwent HPV genotyping, with associations between age and HPV assessed using Cox analyses. Results 4085 men were followed for a median of 48.6 months (range: 0.3–94.0). Significantly lower HPV incidence rates were observed among the oldest age group (55–70 years) for grouped high-risk (incidence rate ratio [IRR]=0.71), HPV16 (IRR=0.54), grouped low-risk (IRR=0.74), and HPV6 (IRR=0.57) infections compared to men ages 18–24. However, incidence of the grouped 9-valent HPV vaccine types remained constant across the lifespan. Likelihood of HPV6 and HPV16 clearance remained constant until age 54, then increased significantly for men ages 55–70 (adjusted hazard ratio [AHR]=1.92 and 1.65, respectively). Conclusions Men remain susceptible to HPV infections throughout their lifespan, highlighting the need for prevention efforts with long-lasting duration.

In order to promote new human papillomavirus (HPV) prevention and detection methods effectively in Mexico, it is important to understand how much the population knows about the virus. This study aimed to determine the demographic and behavioural factors associated with HPV awareness and knowledge in a population of Mexican college students. With a response rate of 77%, data were collected from 1,109 college students aged 17 to 25 years old at the Autonomous University of the State of Morelos in 2006. Students completed a questionnaire that assessed demographic and behavioural characteristics along with questions about HPV. A small percentage (16.9%) of the college students had never heard about HPV. Characteristics associated with not having heard about HPV included being male, not having running water, not having health insurance and not having sexual experience. Students had a median score of 5 out of 10 on an HPV knowledge index based on 10 yes/no questions about HPV developed for this study. Students had higher HPV knowledge scores if they studied health science, or science and engineering, were a 4th year student, had running water at home, had health insurance, or were a female who had had a previous Pap smear. Although most of these Mexican college students had heard of HPV, they had limited knowledge about the virus and prevention strategies. Further research in Mexican college students is needed to explain the variations in HPV knowledge to create appropriate health education programmes.