The purpose of this study was to identify the attitudes and behaviors of faculty and staff that impact the success and persistence of highrisk students. Using an exploratory qualitative approach, 62 successful high-risk students from nine different colleges and universities were interviewed and asked to identify and describe someone on campus who had been most influential in their ability to persist. The 54 campus personnel who were identified by these students were interviewed twice to learn what they do to help students succeed and persist. Seven themes on how college personnel positively influence high-risk student success and persistence were identified.

Antagonism of αvβ6 is emerging as a potential treatment of idiopathic pulmonary fibrosis based on strong target validation. Starting from an αvβ3 antagonist lead and through simple variation in the nature and position of the aryl substituent, the discovery of compounds with improved αvβ6 activity is described. The compounds also have physicochemical properties commensurate with oral bioavailability and are high quality starting points for a drug discovery program. Compounds 33S and 43E1 are pan αv antagonists having ca. 100 nM potency against αvβ3, αvβ5, αvβ6, and αvβ8 in cell adhesion assays. Detailed structure activity relationships with these integrins are described which also reveal substituents providing partial selectivity (defined as at least a 0.7 log difference in pIC50 values between the integrins in question) for αvβ3 and αvβ5.

A mild synthesis of substituted 1,8-naphthyridines from 2-aminonicotinaldehyde is described.

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The success of retention programs for low‐income and minority students is a function of the premises on which the programs are organized and coordinated rather than of the specific services they provide.