Cholelithiasis is a pile of crystals formed by a combination of several elements from the bile in the gallbladder. The incidence of cholelithiasis has been reported to be 5% in the general population, while it is significantly increased in overweight and obese population reaching 45%.  In Indonesia there is less attention because it is often asymptomatic and misdiagnosed. The aim of this study  was to know the relation of increased BMI with the incidence of cholelithiasis at the surgical department of RSI Siti Rahmah Padang within the period in January- June 2018. An observational analytic study was done using the cross sectional approach. Data analysis using univariate and  bivariat  analysis. The  result  of  this  study, out  of  44  patients, the  highest  gender  with cholelithiasis was found in female with 11 people (57.9%), the highest age in cholelithiasis was found 40-49 years 36,8% and There was association between the increased BMI and the incidence of cholelithiasis (p = 0.001).