This study synthesized choline amide as a solvent-free reagent and ion liquid in one pot to directly create benzylamine without producing associated salts. The synthesis of benzyl azide was also carried out with choline azide solventless, and 1,2,3-triazole was prepared in the method mentioned. The synthesis of 1,2,3-triazoles followed the process of a formal benzyl azide cycloaddition. For this purpose, a deep eutectic solvent was used as a catalyst to complete the nitrostyrene process. Both reactions were conducted with a high isolated yield without harmful solvents or catalysts. Eco-friendly and economically feasible, the method also met environmental standards.
In this research, choline chloride/sodium salts are employed as a green medium to produce benzyl amines without salt by-products. In addition, choline chloride/sodium salts are being used as a green medium in producing benzyl azide. The synthesis of 1,2,3 triazoles is followed by a formal cycloaddition process of benzyl azide using nitro-styrene to complete the process. As a result, a component one-pot green fundamental reaction to synthesis of 1,2,3-triazoles has been devised. Furthermore, since no poisonous solvents or hazardous catalysts are employed, the method is environmentally friendly.
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