Feline osteosarcoma (OSA) is a rare tumor in cats. Ninety (62%) of feline OSAs detailed in this study arose from the skeleton, and 55 (38%) arose from extraskeletal sites. Fifty OSAs originated in the appendicular skeleton, and 40 OSAs originated in the axial skeleton. Extraskeletal OSA sites included subcutaneous sites (n=44), with an apparent prevalence for sites commonly used for vaccination. Other locations included ocular/orbital (n=4), oral (n=3), intestinal/omental (n=3), and mammary sites (n=1). Survival data was available for 74 cases. When considered as a group, cats with either appendicular (mean, 11.8 mos) or extraskeletal (mean, 12.67 mos) OSA survived longer than those with axial (mean, 6.07 mos) OSA. Regardless of the type of feline OSA, aggressive surgical excision with or without ancillary therapy appeared to be the most effective form of treatment.

The anaesthetic agent propofol has anticonvulsant properties and has been used in the treatment of refractory status epilepticus in human medicine. This report describes the use of propofol in four cats and one dog with naturally occurring seizures following surgical attenuation of single extrahepatic portosystemic shunts. Two of the animals had seizures that were unresponsive to other anticonvulsants. Subanaesthetic doses of intravenous propofol (1·0 to 3·5 mg/kg boluses and 0·01 to 0·25 mg/kg/minute continuous rate infusions) were used to control the seizures in all animals. However, a good neurological outcome was achieved in only two of the five cases, which is similar to the situation in previous reports.

Propofol is a lipid-based emulsion capable of supporting microbial growth. Administration of a potentially contaminated solution may contribute to surgical wound infection or other patient morbidity or mortality. Strict aseptic technique in the preparation of the solution and prompt disposal of unused drug are imperative to curtail the potential for extrinsic contamination.

This vascular ring anomaly should be considered a possibility in any young dog with esophageal obstruction and a machinery murmur.