To identify predictive factors of prognosis after radiotherapy with concurrent steroid pulse therapy for thyroid eye disease, retrospective analyses were performed among 77 patients. Clinical activity score and magnetic resonance imaging were used to evaluate degrees of orbital inflammation. As a pre-treatment work-up, the thyroid-stimulating antibody (TSAb) level was measured. During a median follow-up of 25.0 months, the 2-year cumulative relapse-free rate (CRFR) was 80.9%. In the univariate analysis, a worse 2-year CRFR was significantly associated with the presence of optic neuropathy (P = 0.001), a higher TSAb rate (P = 0.001), and lower standard deviation (SD) of signal intensity at the extraocular muscle in T2-weighted images (P = 0.006). In the multivariate analysis, TSAb rate and SD affected the CRFR independently. When TSAb activity of 2800% was set as a cut-off at 2 years after treatment, the predictive sensitivity and specificity of relapse were 81.2% and 90.6%, respectively. With regard to SD, the respective sensitivity and specificity values were 81.2% and 82.7% when 100 was set as a cut-off. In conclusion, high TSAb and low SD were significant risk factors for cumulative relapse in orbital radiotherapy. Cut-off values of 2800% for TSAb and 100 for SD may be suitable.

ILD with a UIP pattern or possible UIP pattern by the classification could be a risk factor for AE-ILD in NSCLC patients with ILD.

Our results indicate the existence of threshold levels of serum anti-GM-CSF IgG for the development and persistence of aPAP.

EO sclerotherapy combined with transarterial embolization using NBCA is safe and effective for treating extracranial AVMs with an acceptable risk of minor complications.

We report a case of ruptured renal artery aneurysm successfully treated by emergent transcatheter embolization with microcoils. A 66-year-old woman was referred for emergency treatment after presenting with sudden-onset left flank pain and vomiting. Blood examination showed anemia. Computed tomography demonstrated a partly calcified mass with massive retroperitoneal hematoma. With the diagnosis of a ruptured left renal artery aneurysm, emergency angiography was performed. Left renal arteriography demonstrated a saccular aneurysm at the lower aspect of the renal hilum. A total of five microcoils were placed at the arterial branch, including the orifice of the aneurysm. The first coil was partly lodged in a branch near the orifice of the aneurysm that was used as an "anchor" to prevent subsequent coils from migrating and effectively occluding the parent artery with a short segment. Two branches originating from the renal hilum were preserved. The postoperative course was favorable. Endovascular treatments, including coil embolization, appear to be effective, safe, and less invasive than surgery. This method should be considered as a treatment of choice for ruptured renal artery aneurysm.