Runway performance of rats was studied as a function of reinforcement schedule (100% reward vs. 50% reward) and drug dosage level (10 mg/kg, and 20 mg/kg, i.p. of CDP, and saline). The groups injected with 10 mg/kg of CDP ran faster on initial trials than the other groups, but slightly slower on later trials than the corresponding saline groups. The 50% reward saline group was superior in speeds in early trials but much inferior in later trials to the 100% reward saline group. A similar finding was obtained with 10 mg/kg of CDP. However, the 100% reward group was superior in speeds in final trials than the 50% reward group when both were injected with 20 mg/kg of CDP. As a whole response speeds decreased as the dosage level of CDP increased. The results were discussed in terms of tranquilizing and depressant effects of CDP.

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