New Triple-Helix DNA Stabilizing Agents. -All compounds show triple-helix stabilizing activity. Compounds (I) also show strong duplex stabilizing activity with compound (Ic) being the most selective towards duplex DNA. Compounds (II) do not stabilize duplex DNA, they are completely triple-helix selective. -(STREKOWSKI*, L.; HOJJAT, M.; WOLINSKA, E.; PARKER, A. N.; PALIAKOV, E.; GORECKI, T.; TANIOUS, F. A.; WILSON, W. D.; Bioorg. Med. Chem. Lett. 15 (2005) 4,
magnified imageSynthesis of a series of near‐infrared dimeric dyes is presented. The intramolecular dimers contain two chromophores linked with a conformationally flexible ether or oligoether bridge. Optical properties of the dyes are discussed. J. Heterocyclic Chem., (2009).
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