Afield experiment was carried out during 2018 growing season in Ismailia Governorate, Egypt. The experiment aimed to study the effect of different sources from sediment i.e., Nasser Lake (NLS) and El Shabab Canal (ECS) solely or in combination with natural fertilizers i.e., rock phosphate (RP) and potassium feldspar (KF) + vermicompost (Ver) on availability of P and K, yield and nutrient uptake by maize plants under sandy soil conditions. Application of Nasser Lake sediment mixed with RP+ KF in the presence of Ver. gave the highest vales of stover, grains, ear yield, biological yield and N,P and K-uptake by maize plants compared to different treatments. The application of nature fertilizers i.e., RP, KF and RP+ KF to Nasser Lake sediment and El Shabab Canal sediment increased available P and K in soil after harvest as compared to the untreated ones under application of vermicompost.