The International Association for the Study of Pain (IASP 2011) defines neuropathic pain as “the pain caused by an injury or disease of the somatosensory portion of the nervous system”. The central neuropathic pain is defined as “the pain caused by an injury or disease of the central somatosensory central nervous system”, whereas the peripheral neuropathic pain is defined as “the pain caused by an injury or disease of the peripheral somatosensory nervous system” [1].The peripheral neuropathy describes any affection of the peripheral nervous system. The etiology is vast, there being a number of over 100 possible causes, which causes the global morbidity rate to reach approximately 2.4%. The chronic nature of the pain superposes the everyday routine and leads to the high intake of medication for pain alleviation. The number of cases of neuroplasia has always increased today. This disturbing diagnosis which can potentiate the signs and symptoms of peripheral neuropathy as well as reduce and limit the treatment options associated with neuropathies. The treatment presupposes a multidisciplinary approach, while the solution to prevent complications involves the control of risk factors and pathophysiological treatment.Chemotherapy-induced peripheral neuropathy (CPIN) is a significant disabling symptom that is tightly connected to the administration of neurotoxic cytostatic agents used for the treatment of neoplasia. CPIN compromises the quality of life and produces pain or discomfort [2].I have sought to produce a presentation of the medicated and physical-kinetic treatment options that have proved their effectiveness during clinical studies or random trials and can be applied to cancer patients presenting with symptoms associated with peripheral neuropathy, namely with neuropathic pain, and support it with arguments.

The most common reason for which oncological patients come in the rehabilitation clinics, is pain. This can have various etiologies which are related or not to the neoplasia. In both cases, pharmacotherapy and the physical-kinetic-therapy should be individualized. Over the time, the therapeutic approach for these patients varied due to the fear of not harming. Nowadays, we can count on a few studies when applying various medical treatments and physical-kinetic modalities. An interdisciplinary team should collaborate to treat the pain during the course of illness of an oncological patient. The availability of professionals from major disciplines is essential to offering comprehensive care. However, each specialist must know their medical field in order to give the patient the best treatment. Thus, doctors in other specialties than physical medicine and rehabilitation should provide a more accurate diagnosis of neoplasia as co-present diseases, so the rehabilitation doctors to prescribe proper physical-kinetic procedures and rehabilitation modalities.