Reconstructive surgery of the abdominal and thoracic wall frequently utilizes various materials in order to repair large defects. Polypropylene meshes are an example. In nasal reconstructive surgery they are rarely used for cartilage restoration. The purpose of this paper is to demonstrate the utility of the collagen-coated polypropylene meshes in nasal reconstructive surgery, as they are easy-to-use materials, with reduced incidence of foreign body reactions and with a very small price compared with other compounds. We conducted a literature review on the usage of the collagen-coated polypropylene meshes which also includes a comparison with other types of materials applied for nasal cartilage reconstruction. Moreover, we performed a retrospec - tive study, on the patients hospitalized in the Plastic Surgery Department of the Clinical Emergency Hospital, Bucharest. The best option and in the same time the gold standard for nasal cartilage reconstruction is considered to be autologous cartilage transplantation. In our clinic we observed good results when autologous septalor auricular cartilage grafts were used. Polypropylene is seldom used in nasal reconstructive surgery, having been conducted so far, a limited number of studies related to benefits and disadvantages of this type of material in the accomplishment of the medical devices used as a nasal implant. Polypropylene meshes are largely used in abdominal wall reconstruction and in the surgery for pelvic organ prolapse. In this surgical field, collagen-coated polypropylene meshes are also used, but future studies will demonstrate if they are effective enough in the nasal reconstructive surgery as well.

Hand ischaemia has multiple causes. The Methadone (C21H27NO) - opioid family of drugs and Alprazolam (C17H13Cl1N4) microcrystals, available under the trade name Xanax - benzodiazepine anxiolytic, when using in case of drugs abuser, are very powerful embolic agents which can cause thrombosis of small vessels. Microvascular embolization caused by microcrystals of the injectable powder has contributed to the process of ischaemia. This paper brings into discussions a case of acute ischaemia of the right hand due to intra-arterial injection of suspended tablets of Methadone and Alprazolam microcrystals into the right radial artery, in the distal 1/3 of the forearm.The therapeutic management consisted of restoring the arterial circulation at the ischaemic segment to prevent the propagation of thromboembolic complications by using of i.v. heparine and to preserve the function of the hand by preventing delayed ischaemia and compartment syndrome followed by necrosis. Heparin is a drug widely used in the treatment and prevention of arterial and venous thrombosis. The main effect of heparins lies in their anticoagulant activity. Heparins are involved in different pathways of the coagulation cascade with anticoagulant, antithrombotic, profibrinolytic, anti-aggregative, as well as anti-inflammatory effects.This paper aims to discuss a severe case of ischaemia which demonstrates that intra-arterial injection of oral drugs can lead to limb loss with currently accepted therapy.