The biochemical blood parameters characterizing the students ’nutritional status were evaluated: protein, lipid, carbohydrate metabolism, a number of minerals. The mean values, errors of the mean, median (Me), boundary (Q) and the range of 25–75 percentiles were determined. In 9.1 % of students and 28.6 % of students, the total protein was increased. Creatinine in men was in the upper normal range, in women — at the upper limit of normal, of which 46.2 % was higher than normal. The interval Q25–75 of uric acid in students is determined in the lower normal zone. In 40.0 % of men, decreased high-density lipoprotein cholesterol (Q25–75 corresponded to 1.15–1.79), in women — below normal, Q25–75 5 was 1.3–1.5, decreased in 73.3 %. Me and Q25–75 iron were in the lower normal range; 14.1 % of men and 13.2 % of women are below normal. Me sodium and potassium at the level of the lower boundary of the norm, Q25–75 in the lower zone of the norm: in 16.0 % and 15.4 % of students the levels are reduced. Calcium is slightly above the lower limit of the norm, Q25–75–2.1–2.24, indicating an insufficient intake in the whole group; 25.0 % are below normal. The border of the 25th percentile of magnesium is at the level of the lower border of the norm, in 19.2 % it is reduced. 7.2 % lack of chlorine. Phosphorus is normal, but Q25–75 is in the upper zone; 17.9 % increased. Biochemical markers can identify individuals with metabolic disorders of nutrients. Statistical indicators — the median, the boundaries of 25–75 quartiles and their scope characterize the metabolism of macronutrients and minerals in the group and subgroups of students. Laboratory and mathematical methods can provide a basis for identifying the specific causes of these changes. For this, you can use the questionnaire method of studying the nutrition of students, possibly using the developed questionnaires for a specific situation.

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The prevalence of diseases of the oral cavity in military personnel serving under the contract at various altitudes above sea level in Dagestan was estimated. The working conditions and the influence of physical environmental factors at the effective temperature in the autumn-winter-spring periods of the year are estimated. Professional activity belonged to the category of works IIb. Labor was assessed as harmful 2 degrees (class 3.2). In the winter season, a critical risk of frostbite of the body at medium temperatures and maximum wind was found at heights of 4 m and 1661 m. In the spring and autumn, a moderate risk of frostbite was noted at all altitudes. Dental diseases were registered in the classes «Neoplasms», «Diseases of the digestive system» and «Injuries and poisoning»; their share in the total structure was 15.03%. In the class «Diseases of the digestive system,» the share of dental diseases reached 80.2%. The group «Caries, its complications and other diseases of hard tissues of teeth» occupied the 1st rank place in the structure of morbidity, which is equal to morbidity in the class «Respiratory diseases». The level of oral hygiene is 2.8 ± 0.2 (very low): the teeth are significantly covered with plaque, leading to the progression of pathological processes. Description of the dental status: KPU index (carious, filled, extracted tooth) is 8.5 ± 0.3. The prevailing indicator was «carious», indicating an active carious process in the tissues of the teeth and the «lag» of the treatment, leading to their removal. Military personnel approached a critical indicator of fitness for professional activity. The need for oral sanitation reached 65.5 ± 7.9%. The share of labor losses for dental diseases of the class «Digestive apparatus diseases» reached 3.2%, excluding separation from duty on the day of treatment, of which there are several. The study proves the impact of adverse working conditions on dental morbidity, the need for their assessment to identify risk factors and develop preventive measures.

The Kaliningrad region is known for its specific climate, which can negatively affect the adaptive potential of the body. This manifests in an increased incidence of respiratory diseases and skin conditions. To prevent high morbidity, a plant protein product was included in the diet of first-year university students. This study aimed to assess the effectiveness of this food intervention in preventing the most common diseases among Kaliningrad students. Two groups of university students took part in the food trial. In the control group, catabolic processes prevailed in nutrient metabolism. Disadaptation manifested itself in the metabolism of proteins, vitamins, minerals, hematopoiesis and humoral immunity. Inflammation was indicated by α1- and α2-globulins, a weak immune response, and IgM and IgG. High oxidative stress and low antioxidative ability of blood serum were observed. The plant-based protein product (FP) helped preserve testosterone level and prevent an increase in catabolic reactions. Moreover, it had a positive effect on both red blood cell hematopoiesis (a smaller increase in the average volume of erythrocytes, the same average concentration and content of hemoglobin, an increased relative red cell distribution width (RDW) and white blood cell hematopoiesis (a beneficial effect for the immune system: lymphocytes, the relative content of neutrophils, monocytes, basophils and eosinophils). The stimulation of humoral immunity was evidenced by beta- and gamma-globulins, an active immune response, the level of IgM and IgG, antioxidant protection, reduction of peroxides and an increase in antioxidant activity of blood serum. The 34-week observation showed a 1.7-fold decrease in the incidence of respiratory illnesses and a 5.7-fold decrease in skin and subcutaneous tissue diseases. Acute respiratory infections were reduced 1.8-fold. There were no cases of community-acquired pneumonia in the treatment group, compared with 55.1‰ in the control group. The incidence of respiratory diseases was 3.3–10.6 times lower in the treatment group than in the control group in weeks 6–19. The findings testify to the prophylactic effect of functional food during social adaptation and acclimatization of students.