Background: Dermoscopy can reliably predict the diagnosis of plaque psoriasis. Ultrasonography has been increasingly used in dermatology in inflammatory diseases like psoriasis as a tool for evaluation. Hence, this study was done to evaluate the role of dermoscopy and ultrasonography as prognostic aid in plaque psoriasis. Aims and Objectives: To study the sonographic and dermoscopic findings of clinically diagnosed psoriatic lesions and the changes in the psoriatic lesions if any, with the treatment. How these findings can be utilized to assess the prognosis in these patients. Materials and Methods: The present study comprised 50 patients with clinically diagnosed plaque psoriasis. Lesions were assessed with Dino-Lite digital microscope AM7515MZT, followed by ultrasonography using a 15 MHz probe, and findings were recorded. All the patients included in this study were given appropriate treatment (topical/systemic) for 6 weeks and were followed up twice i.e., at 3 weeks and 6 weeks after initiating treatment. Results: Whitish scales were the most common scale color seen in our study seen in 35/50 patients (70%). All the vascular structures were reddish, red dots and globules being the predominant type and with the improvement of the lesions, brown structures increased. A total of 28 (56%) patients had a regular pattern of vessel arrangement. Mean capillary size was 0.097 ± 0.012 mm that reduced to 0.075 ± 0.019 mm at the end of the third week and 0.027 ± 0.032 mm at the end of 6 weeks. In ultrasonographic assessment, mean epidermal thickness reduced from 0.1008 to 0.0764 cm at third week and 0.068 cm at the sixth week, and mean dermal thickness reduced from 0.2692cm to 0.1906cm at the third week and then to 0.1906cm 0.1806cm at the sixth week. In our study, clinical improvement preceded dermoscopic improvement. Newer structures identified in the study are a perifollicular arrangement of capillaries and the presence of lacunar structures in the healing lesions. Conclusion: The scale distribution, capillary number, and capillary size in dermoscopic assessment, and epidermal and dermal thickness in ultrasonography showed statistically significant changes with treatment and thus may be taken as the prognostic indicators. Thus, both these noninvasive modalities may be useful in the therapeutic monitoring of plaque psoriasis.

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Sir, A 61-year-old female presented to us with a slowly progressive, asymptomatic, localized swelling in the proximal nail fold (PNF) of the left ring finger present for nine months. An examination revealed a discrete, well marginated, skin-colored, firm, non-tender nodule, 8 × 8 mm in size, between the distal interphalangeal (DIP) joint and the PNF of the left ring finger. Besides this, the concomitant nail plate also had longitudinal guttering originating from underneath the PNF and extending until the free edge of the nail plate, corresponding to the possibility of pressure effects of the lesion on the nail matrix (Fig. 1a). Polarized light dermoscopy revealed thick, white, linear structures intermingled with dotted vessels and short, linear, curved, comma-shaped vessels in the center of the lesion (Fig. 2a). High-resolution ultrasonography with power Doppler of the lesion revealed a hypoechoic area without any vascular component (Fig. 2b) and normal appearing interphalangeal joints. Under aseptic precautions, triamcinolone acetonide (TA) at 10 mg/mL was injected intralesionally from its lateral margin until the blanching of the lesion. A transparent, jelly-like material extruded through the entrance of the needle, thus confirming the clinical diagnosis of a digital myxoid pseudocyst (DMP) (Fig. 1b). No recurrence was observed within six months of follow-up (Fig. 1c). A DMP, also called a digital synovial cyst or ganglion cyst, is a benign tumor of the digit. It is not a true cyst as it lacks a cyst wall lined with epithelial cells. It is filled with mucoid materials overproduced by fibroblasts [1]. They arise due to repetitive trauma causing either focal mucinous degeneration of the connective tissue or the leakage of synovial fluid from the DIP joint. Two types of digital mucous cysts are distinguished: the myxomatous, or superficial, type and the ganglion, or deep, type. A DMP may sometimes compress the nail matrix, creating longitudinal depressions in the nail plate, as seen in this case. Nail changes may precede cyst formation by up to six months. Occasionally, the cyst may exert pressure on the nail matrix giving rise to a bluish-red lunula [2]. Salerni et al. described the dermoscopic features of a DMP as bright white areas with a linear, branched, serpentine vascular pattern [3]. Dermoscopy of our case, however, revealed white, linear structures intermingled with dotted vessels and short, linear, curved, comma-shaped vessels. These non-identical dermoscopic patterns could be attributed to the different depth of the DMP in our case to these observed by Salerni et al. The pseudocyst in our case also demonstrated compression effects on the proximal nail matrix indicated by longitudinal guttering in the nail plate, while no such finding was present in the former. In addition, arboriform and polymorphic vascular patterns have also been described. Repetitive puncturing, aspiration, sclerotherapy, and intralesional steroids have been attempted; however, recurrences may develop [4]. Although surgical excision of a DMP with synovectomy shows a lower recurrence rate, it may cause complications such as nail deformities, post-operative pain, and limited post-operative functional use. To conclude, the dermoscopic features of the DMP in the current case may hold an addition to the existing dermoscopic signs, hence aid in the diagnosis of the DMP.