We conclude that regression patterns of tumors in patients undergoing systemic chemoreduction with focal adjuvant treatments predominantly changed over time and their changes are dependent on tumor size, location, and type of treatment. It appears that subretinal seeds, tumor size, and location of tumors are the most important factors predicting tumor recurrence.

Childhood ocular trauma is a preventable cause of visual impairment and blindness worldwide. This prospective study was conducted to explore the profile of eye injuries in pediatric patients referring to a tertiary eye center in Tehran, Iran. Six hundred consecutive pediatric patients aged 17 or less who presented to emergency department of Farabi Hospital were enrolled. Age and sex of pediatric patients, time of trauma, time between trauma and presentation, place of injury, etiology of eye injury, visual acuity, and type of injury based on Birmingham Eye Trauma Terminology were collected. Mean (±SD) age of cases was 7.9 ± 4.8. Male to female ratio was 2.3:1. More than 70 % of the patients presented less than 12 h after ocular trauma. Most injuries occurred at home (57.7 %) followed by street (20.3 %). Twelve patients had visual acuity lower than 0.1 at initial visit. Projectile trauma was the most common cause (35.8 %) followed by blunt trauma (33.3 %). 86.3 % of traumatic events consisted in closed globe injuries. Parents should be involved more effectively in care and supervision of their children especially for boys, at home and on holidays.

The purpose of this study was to describe the results of a new modification of the trabeculectomy technique, sutureless tunnel trabeculectomy without peripheral iridectomy (PI), in a group of patients with chronic open-angle glaucoma (COAG). Patients with uncontrolled COAG who were candidates for trabeculectomy underwent sutureless tunnel trabeculectomy without PI. Patients were examined before surgery and at 1, 3, 6 and 12 months after surgery. Pre- and post-operative data including intraocular pressure (IOP), visual acuity, number of anti-glaucoma medications and intraoperative and post-operative complications were recorded. Surgical success was defined as final IOP < 21 mmHg and > 20 % reduction from baseline (criterion A) and as final IOP < 18 mmHg and > 25 % reduction from baseline (criterion B), without further glaucoma surgery or complications that required returning the patient to the operating room. Success was further classified as complete when these criteria were obtained without medications and qualified with or without medical therapy. Eighteen eyes of 18 patients were recruited into the study. All patients had 6 months of follow-up and 15 patients (83.3 %) completed 12 months of follow-up. Mean (SD) age of the patients was 57.2 (5.7) years. Mean (SD) IOP decreased from 23.7 (4.5) mmHg pre-operatively to 14.7 (3.4) mmHg at final follow-up visit (p < 0.001), and the mean (SD) number of glaucoma medications decreased from 2.89 (0.32) pre-operatively to 1 (0.84) at last visit (p < 0.001). Post-operatively, IOP and number of glaucoma medications were decreased in comparison with baseline at all follow-up visits (p < 0.001 for all visits). Qualified and complete surgical success rates were 78 and 50 % for criterion A, and 72 and 50 % for criterion B. Sutureless tunnel trabeculectomy without PI effectively reduced IOP and number of medications in COAG patients during 6-12 months of follow-up. Further controlled studies are needed to better characterize the safety and efficacy of this technique.