IFAP syndromeis a rare autosomal recessive X-linked disease characterized by the triad of alopecia universalis, severe photophobia, and follicular ichthyosis. It is caused by loss of function of the gene MBTPS2. Its severity varies and there are only a few reports in the literature. We present a patient with characteristic clinical features

Acquired ichthyosis is a known paraneoplastic sign of lymphoproliferative malignancies, with histopathologic findings that are nonspecific, revealing no insinuation of the underlying neoplasm. Mycosis fungoides (MF) is a skin malignancy of T helper lymphocytes with a wide clinical spectrum. Among the atypical variants of MF, there is an ichthyosis- like presentation. However, to date, rare cases of ichthyosiform MF has been reported. We report here the clinical and histopathological features of patient with IMF.

Benign fibrous histiocytoma is one of the most frequent benign neoplasms, the diagnosis of cutaneous benign fibrous histiocytoma is generally easy, however the atypical fibrous histiocytoma is an uncommon, poorly documented variant of cutaneous fibrous histiocytoma,may be difficult to identify, and the diagnosis only confirmed after exhaustive histopathological examination. Recently the dermoscopy has revealed a new dimension of dermoscopic features giant Fibrous Histiocytoma. Our purpose was to report the clinical and dermoscopic characteristics of giant Fibrous Histiocytoma and review the few cases of this variant of Fibrous Histiocytoma reported in the literature.

Benign fibrous histiocytoma is one of the most frequent benign neoplasms ,the diagnosis of cutaneous benign fibrous histiocytoma is generally easy ,however the atypical fibrous histiocytoma is an uncommon, poorly documented variant of cutaneous fibrous histiocytoma,may be difficult to identify, and the diagnosis only confirmed after exhaustive histopathological examination. Recently the dermoscopy has revealed a new dimension of dermoscopic features giant Fibrous Histiocytoma . Our purpose was to report the clinical and dermoscopic characteristics of giant Fibrous Histiocytoma and review the few cases of this variant of Fibrous Histiocytoma reported in the literature.

Poikilodermatous mycosis fungoides (PMF) is a rare clinical variant of early-stage MF with peculiar histological features. Poikiloderma occurs in many different clinical conditions, which makes a diagnosis procedure more complicated. PMF belongs to a group of MF variants with low risk of disease progression.We report 3 cases presented with mottled skin aspect of erythema, poikilodermatous patches (hypopigmentation, hyperpigmentation, atrophy, and telangiectasia) on more than 50-80% of the body. Based on clinical, histopathological, and immunohistochemical findings, we established the diagnosis of PMF