Introduction: Primary cancers of the uterine tube are among the rare tumors of the female genital tract, representing less than 2% of gynecologic malignancies. Cases presentation: We report a case of tubal adenocarcinoma diagnosed incidentally on a hysterectomy specimen in a patient followed at the gynecology department. The patient underwent primary reduction surgery followed by six courses of adjuvant chemotherapy with carboplatin and paclitaxel combined with 23 sessions of radiotherapy and two courses of brachytherapy. The patient is in complete remission with a follow-up of 14 months. Clinical discussion: These cancers of unknown etiology are dominated by adenocarcinoma, the clinical signs are often dissociated, and the preoperative diagnosis is difficult. The diagnosis should be made in the presence of any metrorrhagia associated with leucorrhoea in postmenopausal women. The treatment is similar to that of malignant epithelial tumors of the ovary with a prognosis that depends on the stage of the disease. Conclusion: The diagnosis of cancers of the uterine tube is very difficult to confirm because of the proximity of the uterus and the ovary and to evoke in front of any cellular atypia of the cervico-uterine smear associated with adnexal anomalies. Highlights