In the setting of a challenge competition, some deep learning algorithms achieved better diagnostic performance than a panel of 11 pathologists participating in a simulation exercise designed to mimic routine pathology workflow; algorithm performance was comparable with an expert pathologist interpreting whole-slide images without time constraints. Whether this approach has clinical utility will require evaluation in a clinical setting.

Distributional semantic models derive computational representations of word meaning from the patterns of co-occurrence of words in text. Such models have been a success story of computational linguistics, being able to provide reliable estimates of semantic relatedness for the many semantic tasks requiring them. However, distributional models extract meaning information exclusively from text, which is an extremely impoverished basis compared to the rich perceptual sources that ground human semantic knowledge. We address the lack of perceptual grounding of distributional models by exploiting computer vision techniques that automatically identify discrete “visual words” in images, so that the distributional representation of a word can be extended to also encompass its co-occurrence with the visual words of images it is associated with. We propose a flexible architecture to integrate text- and image-based distributional information, and we show in a set of empirical tests that our integrated model is superior to the purely text-based approach, and it provides somewhat complementary semantic information with respect to the latter.

Colorectal adenocarcinoma originating in intestinal glandular structures is * Corresponding authors Email addresses: k.sirinukunwattana@warwick.ac.uk (Korsuk Sirinukunwattana), n.m.rajpoot@warwick.ac.uk (Nasir M. Rajpoot) Preprint submitted to Medical Image AnalysisAugust 30, 2016the most common form of colon cancer. In clinical practice, the morphology of intestinal glands, including architectural appearance and glandular formation, is used by pathologists to inform prognosis and plan the treatment of individual patients. However, achieving good inter-observer as well as intra-observer reproducibility of cancer grading is still a major challenge in modern pathology. An automated approach which quantifies the morphology of glands is a solution to the problem. This paper provides an overview to the Gland Segmentation in Colon Histology Images Challenge Contest (GlaS) held at MICCAI'2015. Details of the challenge, including organization, dataset and evaluation criteria, are presented, along with the method descriptions and evaluation results from the top performing methods.

Despite a multitude of empirical studies, little consensus exists on whether neural networks are able to generalise compositionally, a controversy that, in part, stems from a lack of agreement about what it means for a neural model to be compositional. As a response to this controversy, we present a set of tests that provide a bridge between, on the one hand, the vast amount of linguistic and philosophical theory about compositionality of language and, on the other, the successful neural models of language. We collect different interpretations of compositionality and translate them into five theoretically grounded tests for models that are formulated on a task-independent level. In particular, we provide tests to investigate (i) if models systematically recombine known parts and rules (ii) if models can extend their predictions beyond the length they have seen in the training data (iii) if models’ composition operations are local or global (iv) if models’ predictions are robust to synonym substitutions and (v) if models favour rules or exceptions during training. To demonstrate the usefulness of this evaluation paradigm, we instantiate these five tests on a highly compositional data set which we dub PCFG SET and apply the resulting tests to three popular sequence-to-sequence models: a recurrent, a convolution-based and a transformer model. We provide an in-depth analysis of the results, which uncover the strengths and weaknesses of these three architectures and point to potential areas of improvement.

Following up on recent work on establishing a mapping between vector-based semantic embeddings of words and the visual representations of the corresponding objects from natural images, we first present a simple approach to cross-modal vector-based semantics for the task of zero-shot learning, in which an image of a previously unseen object is mapped to a linguistic representation denoting its word. We then introduce fast mapping, a challenging and more cognitively plausible variant of the zero-shot task, in which the learner is exposed to new objects and the corresponding words in very limited linguistic contexts. By combining prior linguistic and visual knowledge acquired about words and their objects, as well as exploiting the limited new evidence available, the learner must learn to associate new objects with words. Our results on this task pave the way to realistic simulations of how children or robots could use existing knowledge to bootstrap grounded semantic knowledge about new concepts.