This paper identifies the state of academic facilities and its influence on teachers' job stress in Tamale polytechnic. The study adopted a case study approach because it probes a specific tertiary institution in Ghana. Quantitative research method was adopted. Accidental sampling technique was used to draw sample from the population. The research used questionnaire as the main data collection instrument. Total of 114 retrieved questionnaires gave 82.6% response rate. Cronbach's Alpha and KMO was used to test sample reliability and adequacy which yielded coefficients ranging from 0.734 to 0.755. Data were analyzed using inferential statistics, with Pearson Product Moment Correlation and multiple regression models as analytical tools. Hypothesis was tested at a significant level of 0.01 and 0.05. Results revealed a significant relationship of variable for status of school facilities and teacher academic stress sources. Results of hypothesis tested show that status of school facilities influence teacher job stress significantly. It was concluded that inadequate or complete lack of academic facilities for state of the time would not only impair academic productivity, but rather exert undue stress on teachers and available facilities, and recommended that the development priorities of the institution should be staffstudents oriented.