Background: Oxidative stress, genetic expression changes, and decomposition of the blood-brain barrier have been shown to be caused by exposure to radiofrequency radiation (RFR); therefore, the search for drugs or food products that offer some protection from these effects has attracted interest. Lepidium meyenii (maca) is a native Andean plant known for its effects on the female reproductive system as well as its immunomodulating, energizing, antioxidant, and nutritive properties due to its high concentration of alkaloids, amino acids, glucosinolates, fatty acids, and macamides. Objectives: We aim to determine the effect of dietary maca supplementation on spatial memory and cerebral oxidative damage in rats with induced menopause and/or with exposure to mobile phone radiation. Method: Female rats divided into 6 groups (six rats in each group): control or not ovariectomized (O-), ovariectomized (O+), ovariectomized + estrogen (O+E+), ovariectomized + estrogen + irradiated (O+E+I+), ovariectomized + maca (O+M+), and ovariectomized + maca + irradiated (O+M+I). Rat spatial memory was tested using the Morris water navigation task. Rats were sacrificed, and cerebral malondialdehyde was measured. Results: After exposure to mobile phone radiation, the group supplemented with maca showed improved spatial memory and lower levels of malondialdehyde than the estrogenized group. Conclusions: Our results suggest that consumption of maca has a positive effect on the maintenance of memory and decreases oxidative stress caused by mobile phone radiation. However, it is necessary to extend this work using a larger sample size.

Introducción. Hacia finales del último mes del 2019, se identificó un nuevo coronavirus altamente contagioso en China provocando el inicio de una nueva pandemia. Millones de infectados y miles de muertes es el resultado de la infección por el SARS-CoV-2; diferentes estrategias terapéuticas se han propuesto para su tratamiento, una de ellas ha sido la ivermectina, provocando discrepancias en la comunidad médica en relación a su uso. Nos propusimos revisar la evidencia científica disponible sobre el uso de la ivermectina en el contexto de la COVID-19 en humanos. Se realizó una búsqueda de bibliografía en las siguientes bases de datos: Pub Med, Web of Science, Cochrane, Clinical Trials e ISRCCTN usando expresiones de búsqueda que incluyan los siguientes términos: ivermectina, antiviral, virus, covid-19 y/o SARS-CoV-2. No hay evidencia científica que respalde el uso de ivermectina como tratamiento y/o profilaxis para la infección por SARS COV-2.