To develop, implement and evaluate a 'Shark Tank' style co-curricular activity focusing on creating a new clinical pharmacy service, including assessing student performance and determining the effect of the activity on students' perceptions of innovation as it applies to their own future practice and pharmacy practice in general. Methods. Second year pharmacy students participated in an optional 'Shark Tank' style co-curricular activity and worked in teams to develop a clinical service. A team of faculty graded students according to a CAPE-mapped rubric to determine the winning team. A pre-and post-survey was administered to gather information about changes in perceptions of innovation and entrepreneurship. Results. Student groups received higher scores on their ability to present the background and need for their clinical service, and lower scores in areas such as tracking outcomes and predicting challenges. After completing the activity, 96.7% of responding students agreed that the activity gave them a better understanding of pharmacists' roles in establishing new clinical services and 86.7% stated they intend to actively seek out new clinical pharmacy service opportunities in their future career. Conclusion. Survey results demonstrate that students understand the importance of innovation and entrepreneurship in pharmacy practice, and almost all students felt that the activity gave them an even better understanding of the pharmacist's role in clinical service development. This activity can serve as a blueprint for schools of pharmacy looking to incorporate creative and fun methods of exposing students to innovation and entrepreneurship activities.

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