In patients with MS, sexual dysfunction has a much larger detrimental impact on the mental health aspects of HrQoL than severity of physical disability.

The 25-item MSRS assesses several psychological, social, and physical factors associated with resilience in PwMS, and may be a helpful tool in identifying individuals in need of additional assistance or support. (PsycINFO Database Record

Cognitive dysfunction is observed in about half of people with multiple sclerosis (MS), and MS health-care professionals face the challenge of screening, assessing, and treating patients for cognitive problems. Considering the inconsistent or limited empirical evidence to assist in this task, a multidisciplinary consensus conference of MS experts, sponsored by the Consortium of Multiple Sclerosis Centers (CMSC), was held on September 24, 2010, to address these issues. Key articles from the literature on these topics were distributed prior to the meeting, and CMSC member professionals were surveyed on clinical practices related to screening, assessment, and treatment for cognitive problems. The purpose of the meeting was threefold: 1) to achieve a multidisciplinary perspective on practices for screening, monitoring, evaluating, and treating MS patients for cognitive problems; 2) to propose consensus candidate measures for screening and/or monitoring for cognitive problems in MS that neurologists or nurses might administer on a regular basis; and 3) to propose consensus treatment approaches from a multidisciplinary perspective. This article summarizes the conclusions of the conference participants and provides preliminary suggestions for screening and brief assessment. Int J MS Care. 2012;14:58-64. Multiple sclerosis (MS) is an immune-mediated demyelinating disease of unknown etiology in which there is a T cell-mediated attack on oligodendrocyte and myelin epitopes in the central nervous system (CNS). As a result, MS patients may have localized areas of demyelination in the CNS, as well as damage to or loss of proximal gray matter. The symptoms of MS run a wide gamut, depending on the location of the lesions. One category of symptoms affecting a large portion of the MS population is cognitive dysfunction, with estimated rates ranging from 43% to 70%. 1,2 Cognitive dysfunction in MS spans the domains of visuospatial processing, information processing speed, working memory, executive functioning, verbal and visual learning, and episodic memory.Symptoms of cognitive dysfunction can appear early, even before patients have reached the full criteria for MS. 3 Even with mild cognitive impairment, patients can have significant functional disability. 4 Cognitive dysfunction can interfere broadly with patients' lives, causing a decrease in quality of life, 2 impairments in social functioning, 5 and problems with employment. 6 Thus, it is necessary to develop widely used screening tools, assessments, and interventions that have demonstrated reliability and validity. However, existing literature on CONSENSUS STATEMENT

Objectives Persons with multiple sclerosis (MS) can face a number of potential healthcare-related barriers, for which mobile health (mHealth) technology can be potentially beneficial. This review aimed to understand the frequency, current uses, and potential barriers with mHealth usage among persons with MS. Methods A query string was used to identify articles on PubMed, MEDLINE, CINAHL, and IEEE Xplore that were published in English between January 2010 and December 2019. Abstracts were reviewed and selected based on a priori inclusion and exclusion criteria. Fifty-nine peer-reviewed research studies related to the study questions are summarized. Results The majority of persons with MS were reported as using smartphones, although rates of mHealth utilization varied widely. mHealth usage was grouped into 3 broad categories: (1) disability and symptom measurement; (2) interventions and symptom management; and (3) tracking and promoting adherence. While there have been an increasing number of mHealth options, certain limitations associated with MS (eg, poor dexterity, memory problems) may affect usage, although including persons with MS in the design process can address some of these issues. Discussion Given the increased attention to mHealth in this population and the current need for telehealth and at home devices, it is important that persons with MS and healthcare providers are involved in the development of new mHealth tools to ensure that the end product meets their needs. Considerations for addressing the potential mHealth use barriers in persons with MS are discussed.