Introduction: Hemiplegia is the first cause of physical and mental handicap in adults with an incidence of 1.5 per 1000. Death arises principally during the first six months; the mortality rate is estimated at 25% for the first month. There are many rehabilitative methods for this handicap but this research was focused on the Proprioceptive Neuromuscular Facilitation (PNF). This PNF aims at improving motor responses but it is not yet effectively implemented in the rehabilitative protocol of post stroke hemiplegic patients in the Bafoussam Regional Hospital. The main objective was to evaluate the impact of PNF in the rehabilitation of post stroke hemiplegic persons. Methods: This study was an interventional study which took place at the Regional Hospital of Bafoussam. We included in this study post stroke hemiplegic persons undergoing rehabilitation in the physiotherapy unit and who consented to participate. We had 2 groups: the case group which received PNF and the control group which received only the classical protocol of the hospital. Results: The results of this study show that both PNF and classical therapy improved muscular strength, range of motion, equilibrium and functional independence but, the PNF+ group generally had better scores especially at the level of functional independence with a statistically significant difference (p-value=0.0194). Conclusion: PNF in this study seems to be more efficient in the management of post stroke hemiplegia in this context and should be recommended in the Physiotherapy unit of the above hospital. There is also need for similar studies to be implemented in other hospital contexts in the country and with larger sample sizes to better appreciate this efficiency.