Practical
Pd-catalyzed 2-pyridones were designed to achieve chromeno[2,3-b]pyridine-2-ones. The reaction proceeds through domino
nucleophilic addition and decarboxylative arylation, respectively.
This methodology offers a moderately efficient approach to construct
the bioactive, fused-heterocyclic skeletons via selective C–O
bond formation and decarboxylative arylation in a single step with
high selectivity and good yields.
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