This study is the first known to use network meta-analysis to simultaneously evaluate the effectiveness of interventions to increase the prevalence of functioning smoke alarms in households with children. The authors identified 24 primary studies from a systematic review of reviews and of more recently published primary studies, of which 23 (17 randomized controlled trials and 6 nonrandomized comparative studies) were included in 1 of the following 2 network meta-analyses: 1) possession of a functioning alarm: interventions that were more "intensive" (i.e., included components providing equipment (with or without fitting), home inspection, or both, in addition to education) generally were more effective. The intervention containing all of the aforementioned components was identified as being the most likely to be the most effective (probability (best) = 0.66), with an odds ratio versus usual care of 7.15 (95% credible interval: 2.40, 22.73); 2) type of battery-powered alarms: ionization alarms with lithium batteries were most likely to be the best type for increasing functioning possession (probability (best) = 0.69). Smoke alarm promotion programs should ensure they provide the combination of interventions most likely to be effective.

BackgroundThere exist no recommendations as to how aggregate research results should best be disclosed to long‐term cohort participants.ObjectiveTo study the impact of cohort results disclosure documents of various kinds on participants’ satisfaction.DesignRandomized study with a 2x2 factorial design.Setting and participantsThe GENEPSO‐PS cohort is used to study the psychosocial characteristics and preventive behaviour of both BRCA1/2 carriers and non‐carriers; 235 participants wishing to receive ‘information about the survey results’ answered a self‐administered questionnaire.InterventionsThe impact of providing the following items in addition to a leaflet about aggregate psychosocial research results was investigated (i) an up‐to‐date medical information sheet about BRCA1/2 genetic topics, (ii) a photograph with the names of the researchers.Main outcome measuresSatisfaction profiles drawn up using cluster analysis methods.ResultsProviding additional medical and/or research team information had no significant effect on satisfaction. The patients attributed to the ‘poorly satisfied’ group (n = 60, 25.5%) differed significantly from those in the ‘highly satisfied’ group (n = 51, 21.7%): they were younger [odds ratio (OR) = 0.96, 95% confidence interval (0.92–0.99), P = 0.028], less often had a daughter [OR = 4.87 (1.80–13.20), P = 0.002], had reached a higher educational level [OR = 2.94 (1.24–6.95), P = 0.014] and more frequently carried a BRCA1/2 mutation [OR = 2.73 (1.20–6.23), P = 0.017].ConclusionsThis original approach to disclosing research results to cohort participants was welcomed by most of the participants, but less by the more educated and by BRCA1/2 carriers. Although an easily understandable document is necessary, it might also be worth providing some participants with more in‐depth information.

Background The National Organized Colorectal Cancer Screening Program (DOCCR) was introduced in 2008. The participation rate in France is much lower than the European recommendations (33.5% versus 45%). There are significant disparities across France. The objective was to assess whether there are disparities in participation rates within the Bouches-du-Rhône(BdR) department and to study the possible correlation of these geographical areas with their level of precariousness. Methods Based on data collected by the ARCADES association (management structure in charge of cancer screening in the BdR region), 325,207 people in 2012 and 489,953 in 2017 were invited to participate in the DOCCR. The participation was analysed in two aspects: participation rate (TP) (test carried out) and participation rate of those who took a test or expressed a justified refusal (TPJ) (personal or family history, other test under 2 years old, colonoscopy under 5 years old). An average precariousness rate was also assessed per municipality based on 2012 INSEE data for the age group concerned. Results The TP were 18.9% in 2012 and 14.4% in 2017; the TPJ were 22.8% and 16.4% respectively and differs significantly between the municipalities in the department (p < 0.001). The average precariousness rate observed in our population was 12.3 (±8.2). The TPJ is inversely correlated with the precariousness rate: the higher the latter, the lower the participation rate (R=-0.58 in 2012, R=-0.539 in 2017; p < 0.05). The average participation rate whatever the year is lower for municipalities with a precariousness rate below the median (19.2 ± 2 versus 16.9 ± 3.5 for the year 2017). Conclusions Participation rates in 2012 and 2017 are lower than the European recommendations. The participation is significantly related to the average rate of precariousness; the most vulnerable participate less well. Specific actions towards the most vulnerable are to be considered in order to improve adherence to the DOCCR. Key messages The participation organized colorectal cancer screening program is significantly related to the average rate of precariousness. Specific actions towards the most precarious are to be considered in order to improve adherence to the DOCCR.