BackgroundStudies that aimed at comparing the clinical presentation of influenza patients across virus types and subtypes/lineages found divergent results, but this was never investigated using data collected over several years in a countrywide, primary care practitioners-based influenza surveillance system.MethodsThe IBVD (Influenza B in Vircases Database) study collected information on signs and symptoms at disease onset from laboratory-confirmed influenza patients of any age who consulted a sentinel practitioner in France. We compared the clinical presentation of influenza patients across age groups (0–4, 5–14, 15–64 and 65+ years), virus types (A, B) and subtypes/lineages (A(H3N2), pandemic A(H1N1), B Victoria, B Yamagata).ResultsOverall, 14,423 influenza cases (23.9% of which were influenza B) were included between 2003–2004 and 2012–2013. Influenza A and B accounted for over 50% of total influenza cases during eight and two seasons, respectively. There were minor differences in the distribution of signs and symptoms across influenza virus types and subtypes/lineages. Compared to patients aged 0–4 years, those aged 5–14 years were more likely to have been infected with type B viruses (OR 2.15, 95% CI 1.87–2.47) while those aged 15–64 years were less likely (OR 0.83, 95% CI 0.73–0.96). Males and influenza patients diagnosed during the epidemic period were less likely to be infected with type B viruses.ConclusionsDespite differences in age distribution, the clinical illness produced by the different influenza virus types and subtypes is indistinguishable among patients that consult a general practitioner for acute respiratory infections.

This paper focuses on the use of free–free resonance testing (FFR testing) applied to the characterization of stabilized silt and sand specimens treated in situ by deep soil mixing. The aim of FFR testing is to measure the natural frequencies of free vibration of the tested specimen. Compression and shear wave velocities, seismic moduli and Poisson’s ratio can be determined from these frequencies. Block samples were taken from soil–cement columns installed at a test site near Paris, France. Specimens of 100 by 50 mm (height to diameter ratio of 2) were cored from these blocks and submitted to FFR testing in the laboratory. The measured resonant frequencies were very repeatable for all specimens tested, validating the use of free–free resonance as a rapid testing method for the characterization of fairly heterogeneous stabilized soil specimens. It was found that both P-wave and S-wave velocities increase nonlinearly with unconfined compressive strength. A linear correlation between strength and dynamic stiffness was observed. Free–free resonance test results can be correlated with index parameters such as density and porosity and used for preliminary assessments of static stiffness as all these parameters varied linearly with measured wave velocities.

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