Background: Retinoblastoma, although a rare pediatric cancer, can lead to disastrous outcomes if not managed early. This mishap often happens in developing countries. Conversely, early diagnosis and treatment of retinoblastoma in developed countries were associated with a surge in RB1 gene carriers.Aim: The authors aimed to evaluate the incidence of retinoblastoma in the Lebanese population aged between 0 and 19 years according to age, sex, and other variables and compare the age-standardized incidence rates with regional and worldwide countries.Methods: Data were retrieved from the National Cancer Registry (NCR) of the Ministry of Public Health (MOPH). Subsequently, incidence rates, age-standardized rates, and fictional incidence rates excluding the emigrant population were calculated. Retinoblastoma trends were found using the Joinpoint regression program software.Results: From the 38 cases of retinoblastoma recorded in the nine years cohort, 29 cases occurred in the 0-4 age group, and age-standardized rates were 2.8 and 3.6 per million person-years for the 0-19 and 0-14 age groups, respectively. When the refugee population was excluded, the ASR 0-19 almost doubled from 2.8 per million person-years to 5.16 per million person-years. Joinpoint regression revealed that retinoblastoma trends were divided into two segments showing a decrease from 2005 until 2011 and a rising trend in 2011-2015. When compared to other countries in the region, Lebanon had low-intermediate 0-19 ASRs.Conclusion: Retinoblastoma incidence in Lebanon is in the lower margin of the worldwide average and could be underestimated due to the underdiagnosis in the refugee population. Efforts are being deployed to overcome the financial barriers in the treatment of retinoblastoma by coordinating with neighboring Arab countries.
BackgroundLittle is known about self-mutilation and suicide-related research in the Arab world. AimWe aim to quantify research activity related to suicide and self-mutilation, according to socio-economic factors, and assess inter-regional collaborations and trends of topics in the Arab world in the last 16 years. MethodsA search was conducted through the PubMed database to find articles related to suicide and self-mutilation, according to author affiliation in the 22 Arab countries between 2004 and 2019 (inclusive), and standardized according to mean population, suicide, and self-mutilation disability associated life years (DALY), and gross domestic product (GDP). VOS Viewer was used for keyword and organization co-occurrence analysis. ResultsOnly 0.61% of articles related to suicide and self-mutilation published between 2004 and 2019 were of Arab origin, compared to 1.76% in South America and 7.94% in Far East Asia. Suicide and self-mutilation articles make up 0.09% of the total publications in the Arab region. Egypt, Saudi Arabia, and Lebanon had the highest number of published articles related to suicide and self-mutilation. When comparing publications per million persons, Lebanon and Kuwait ranked first with 5.15 and 3.40 publications per million persons. Lebanon showed the highest number of publications per USD billion GDP, with 0.75 publications. The highest number of publications per 1% self-injury-related DALY was recorded in Saudi Arabia, with 46.97 publications. In recent years, VOS Viewer revealed poor inter-regional collaborations and a modest but increasing trend towards depression, poisoning, and cross-sectional studies. ConclusionDespite increasing publications, the region still lags in terms of suicide and self-mutilation research activity. A pan-Arab strategy should be implemented to refine suicide-related research and increase mental health awareness.
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