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The aim of this study was to assess, via multi-slice helical computerized tomography (CT), the influence of the pure-phase multiporous beta-tricalcium phosphate (beta-TCP) on bone density around dental implants inserted into fresh extraction sockets. Twenty-eight patients (18 women and 10 men), indicated for extraction of their lower premolars and insertion of immediate dental implants, were included in this study. They were randomly divided into two equal groups (14 patients each). Group A received immediate dental implants without any filling material around the implants, while in group B, a pure-phase multiporous beta-TCP was gently packed into the bone gaps around the implants. Three and 6 months after loading the implants, a CT, sagittal and coronal, was made to measure the bone density around the implants. The results of the current study have shown that the mean values of the bone density measurements around the implants in group A were 1150 ± 205 (range, 645-1460) at 3 months and 1245 ± 165 (range, 884-1650) at 6 months after loading the implants. In group B, the mean values of the bone density measurements around the implants were 1280 ± 320 (range, 876-1790) and 1490 ± 358 (range, 1061-1965) at 3 and 6 months after loading the implants, respectively. The statistical analysis of the collected data showed a significant increase in the bone density measurements from 3 to 6 months only in group B (P < .05). Also, the difference between group A and B in the bone density measurements around the implants was statistically significant (P < .05) at only 6 months after loading. On the basis of the results presented in this study, it may be possible to mention that the pure-phase multiporous beta-TCP may enhance the bone density when inserted into the bone gaps around immediate dental implants.

The results of this study support the view that the use of the pedicled BFP is a durable, straightforward, convenient, and reliable method for the treatment of a large OAF.

It can be concluded that direct application of the PRP along the fracture lines may enhance the bone regeneration in mandibular fractures.