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Although chemical hair straightening application has a beneficial effect on hair shafts, some side effects may occur after. Hence, it is necessary to develop a more safe tool.

Background Skin manifestations in diabetes mellitus (DM) are quite common. Skin changes can manifest in the prediabetic stage, in the acute metabolic situation and in the late diabetic degenerative stage. Objective To study the prevalence and the pattern of cutaneous manifestations among diabetic patients to aid in better management of diabetic skin diseases. Patients and methods One hundred patients with DM having at least one skin manifestation were selected and subjected to a detailed dermatological and systemic examination, and the findings were recorded. Blood samples were obtained for random blood glucose level. Results The most prevalent findings were cutaneous infections (40%), followed by pruritus (11%), local reactions at the site of insulin injection (8%), vitiligo (8%), diabetic dermopathy (7%), periungual telangectasia (6%), and xanthelasma (5%). The prevalence of skin manifestations was higher as the duration of diabetes increased and was more in type II than in type I diabetic patients. Conclusion The early detection of skin manifestations in DM is of prime importance to be able to avoid and/or properly manage the complications and prevent disability.

BackgroundStriae distensae or stretch marks, although not a health risk, are of significant cosmetic concern as it affects the patient's psychological condition. Although many treatment modalities have been attempted with variable results, there is no standard treatment modality for it. Objective To compare the efficacy of a microneedling system (dermaroller) when used alone or combined with 15-30% trichloroacetic acid (TCA) in the management of striae rubra. Patients and methodsThis clinical trial included 30 female patients with abdominal striae rubra treated with a dermaroller alone on the left side of the abdomen (GI) and with a dermaroller + 15-30% TCA on the right side of the abdomen (GII). Patients were treated for six sessions at 3-week intervals. We assessed the clinical features (length, width, color, and texture) of striae in each group at every session and 3 weeks after the end of the sessions (follow-up). The response to treatment was assessed objectively by the treating physicians and skin biopsies stained with hematoxylin and eosin and picrosirius red stains. Subjective assessment of the clinical photographs and patient satisfaction scores was carried out by two uninvolved blind dermatologists at every session. Results A comparison between GI and GII at the follow-up session revealed statistically significant differences in length (P = 0.002), width (Po0.001), color, and texture (P = 0.049 and 0.041, respectively). More improvement in the striae was noted in GII, as 19 (63.3%) patients showed good to excellent improvement compared with 10 (33.3%) patients in GI. Skin biopsies in GII showed increased epidermal thickness after treatment (Po0.005). Collagen content was increased after treatment in both groups. Side effects including transient erythema, edema, burning pain, and hyperpigmentation were observed more in GII with increasing concentration of TCA peeling. ConclusionBoth dermaroller and dermaroller + 15-30% TCA are effective treatment modalities for striae rubra. However, dermaroller + 15-30% TCA gives better results and dermaroller alone has fewer side effects.

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