Background Dizziness, including vertigo, affects approximately 15% to over 20% of adults each year. A significant proportion of patients with vertigo develop secondary psychiatric disorders throughout their disease. On the other hand, patients with psychiatric disorders frequently report dizziness as a co-occurring symptom of their illness. The purpose of this study was to screen the prevalence of depression and anxiety indices in dizzy patients and their relation to the severity of their dizziness handicap by administering two different questionnaires: The dizziness handicap inventory (DHI) and the Hospital Anxiety and Depression Scale (HADS).  Results Psychological assessments revealed that 49% of the study group was normal, 29% had anxiety, 7% had depression, and 15% had both anxiety and depression. Besides, vestibular neuritis was associated with a higher mean anxiety score, whereas Meniere's disease was associated with a higher mean depression score.  Conclusion As this study has shown, there was a statistically significant positive correlation between anxiety and depression scores and physical, emotional, functional, and total DHI scores. Screening and treatment of co-morbid mental health disorders are critical for appropriate management of vertigo disability that leads to a higher quality of life and fewer complications.

Aim:To evaluate hidden hearing loss (HHL) in industrial workers using the extended high frequency audiometry(EHFA) and ABR wave I amplitude during routine follow-up visits to the audiology clinic to identify and managehidden hearing loss as early as possible. Materials and Methods: This study is comprised of two groups: study group which consisted of 50 adultindustrial workersattending the audio-vestibular medicine clinic for their routine follow-up visits and control group which consisted of 20 adults with bilateral normal peripheral hearing in the frequency range of 250-8000 Hz, including 3 and 6 kHz without any history of occupational noise exposure. Both groups were age and sex-matched. Results: Results showed statistically significant differences between patient and control groups as regards thresholds of EHFA at 12 and 16 KHz. In addition, there was statistically significant reduction in ABR wave I amplitudes between the two groups. Conclusion: Combining extended high-frequency audiometry and ABR amplitude measurements as two methods for early detection of audibility declines upon exposure to noise as well as an early warning of hair cell damage and loss is advised.

Background: There is a substantial prevalence of psychopathology of anxiety or depression, and several mental problems in many tinnitus groups. Aim of The Work:To use the Tinnitus Functional Index (TFI) as a valid scale for assessing the overall severity of tinnitus and detailed analysis of multiple severity domains, and correlating it to The Hospital Anxiety and Depression Scale (HADS) scores in order to establish a potential correlation between tinnitus and anxiety and depressive disorders in order to improve tinnitus clinical implications and rehabilitation. Subjects and Methods: A cross-sectional study design was designed to explore the prevalence of psychological disorders among patients with tinnitus and to analyse its multiple severity domains thresholds using both TFI & HADS questionnaires. Results: There was a positive correlation between both anxiety & depression subscales of (HADS) and total TFI scores with its subscales. Conclusion: Despite the limited understanding of psychological concerns in tinnitus patients, the prevalence of anxiety disorders in these populations has increased. The reported co-occurrence might impact the clinical course of tinnitus and its management.

Extracellular polymeric substances (EPSs) are ecologically friendly natural polymers produced by microorganisms in the surrounding media. Due to their varied chemical composition, exopolysaccharides are widely used in a variety of applications, including food, pharmaceuticals, and medical applications. In this work, thirty-six isolates of Actinobacteria isolated on starch nitrate medium from various locations of Egyptian soils were assessed for exopolysaccharide (EPS) synthesis. The isolated bacterium that produced the most EPS was Actinobacterium 10 (Streptomyces plicatus). Several culture and environmental parameters were investigated during the microbial growth in submerged culture to enhance bacterial growth and EPS production. The optimal crude EPS generation of 8.62 g/l was achieved after 7 days of incubation at 20 g/l starch concentration, at 35 °C and pH 7, under shaking at 120 rpm, with the most significant impacts. The findings of this study pave the door to produce large quantities of EPS from soil Actinobacteria for food and medicinal purposes.