Introduction: Coronavirus disease 2019 (COVID-19) is an illness due to severe acute respiratory syndrome, symptoms and severity of disease varies from patient to patient, autoimmune hemolytic anemia (AIHA) in children with COVID-19 is rare. Case presentation: A 12-year-old female presented with fever, headache, myalgia, and hematuria. At admission, she was hemodynamically stable, severe anemia was present, and severe acute respiratory syndrome coronavirus 2 infection was confirmed by RT-PCR. The diagnosis of AIHA was confirmed and treated. Discussion: There are few reports of patients with AIHA and COVID-19. However, the majority of patients in these reports also have autoantibodies and other underlying conditions known to be associated with the development of AIHA. Conclusion: In this current pandemic, it should be taken into account that previously healthy children with severe acute respiratory syndrome coronavirus 2 infection have been found to have severe hemolytic anemia in the absence of COVID-19.

Introduction and importance Chickenpox (Varicella) is a benign illness caused by varicella-zoster virus, predominant in childhood. Chicken pox related neurological complications are seen in less than 1% cases of chickenpox. Cerebral Venous thrombosis due to primary (VZV) infection is very rare, and it may occurs secondary to primary or re-activation the virus. Case presentation We report a case of 5-year-old female complained of ataxia, vomiting, headache, and drowsiness 7 days after the onset varicella zoster infection. She had vesicular lesions with scab over the trunk and limbs. Clinical discussion Neurological examination revealed left hemiparesis. Her blood counts and metabolic parameters were normal. Computed tomography brain showed hemorrhagic infarct in the left temporo-parietal region. Coagulation profile was normal. Magnetic resonance imaging (MRI) brain revealed hemorrhagic infarct in the same region. Magnetic resonance Venogram showed thrombosis of left transverse sinus and sigmoid sinus and internal jugular vein. VZV- IgG antibody was positive but CSF VZV PCR (Polymerase chain reaction) was found to be negative. Intravenous acyclovir for 15 days, and low-molecular-weight heparin for 3 days overlapped with oral Warfarin for 3months,. After 3 months follow up, the patient experienced a complete recovery. MRI repeated after 3 months showed recanalization of the sinuses. Conclusion The pathogenic link of occurrence of CSVT after VZV infection is unclear, but some articles showed that it is related to direct endothelial damage by the virus. Early recognition of this complication of VZV infection and prompt treatment is essential to prevent catastrophic complications.