As doenças autoimunes são patológias onde o próprio organismo desenvolve uma resposta imune contra um autoantígeno (autológo). Existem vários fatores que desencadeiam essa perca de tolerância ao próprio organismo, como por exemplo, os genéticos. O risco hereditário para a maioria dessas patológicas é atribuível a múltiplos loci, cuja maior contribuição é feita pelos os genes do MHC. Objetivou-se, com esta pesquisa, fazer levantamento de casos diagnosticados de Doenças Autoimunes (DAIs) e Imunodeficiências Primaria (IP) em cidades localizadas no Agreste e na capital de Pernambuco. No Agreste, foram selecionadas quatro cidades para o desenvolvimento desse trabalho. Após a liberação da carta de anuência, e aprovação do comitê de ética e pesquisa (CEP UNIFAVIP), iniciou a pesquisa. Foram analisados 1 mil prontuários, de pacientes diagnosticados com estas patologias, entre os anos de 2016 a 2018. Desses, apenas 94 prontuários foram utilizados por conterem informações completas para os resultados deste trabalho. Foram identificados 93 registros de DAIs e 1 de IDP. Mesmo não tendo sido um dos objetivos propostos, inicialmente pela pesquisa, foram constatadas inúmeras dificuldades tanto no acesso quanto na interpretação dos prontuários, como por exemplo dados incompletos e SID da doença diagnosticada.  A doença celíaca foi a patologia que apresentou maior prevalência no agreste pernambucano.

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Objective: To demonstrate a general view on the clinical and morphological aspects in children with Hydranencephaly. Methodology: This is a study that uses the systematic review as a method. Data collection took place in September 2019 through the SciELO and EBESCO databases with the following descriptors:"hemihydranencephaly", '' Rare diseases '', 'malformation'. For the selection of articles, the following were used: inclusion criteria: articles in Portuguese, English, full articles that portray the theme related to the literature review and articles published and indexed in the referred databases in the period from 2007 to 2019. Results and Discussion: Hydranencephaly is a condition that in Most are lethal with exceptions, this malformation of the central nervous system occurs after the closure of the neural tube, defined as total or partial absence of cerebral hemispheres, the entire cortex that would be irrigated by the carotids is nonexistent. however, the brainstem, diencephalon and part of the occipital cortex, irrigated by the posterior cerebral arteries, are formed and may exhibit electrical activity. In some cases they have severe neurological sequelae, psychomotor disability, visual impairment, deafness and progressive macroencephaly. Conclusion: Patients with this rare condition are subjected to several surgeries and antibiotic therapies for prolonged periods in an attempt to provide the best survival for the patient. irrigated by the posterior cerebral arteries, are formed and may exhibit electrical activity. In some cases they have severe neurological sequelae, psychomotor disability, visual impairment, deafness and progressive macroencephaly. Conclusion: Patients with this rare condition are subjected to several surgeries and antibiotic therapies for prolonged periods in an attempt to provide the best survival for the patient. irrigated by the posterior cerebral arteries, are formed and may exhibit electrical activity. In some cases they have severe neurological sequelae, psychomotor disability, visual impairment, deafness and progressive macroencephaly. Conclusion: Patients with this rare condition are subjected to several surgeries and antibiotic therapies for prolonged periods in an attempt to provide the best survival for the patient.

This research addresses how nurses can act to prevent the fall of the elderly. The study is justified by the fact that the population over 60 years to be the most vulnerable to suffer falls and this realiade has increased over the past two decades in Brazil, and the elderly hospitalization increase due to this type of accident. This is a field research, quantitative and explanatory held at the Regional Hospital of the Wasteland Dr. Waldemiro Ferreira in Caruaru, Pernambuco. They interviewed ten nurses. The results indicate that nurses work in perspective to guide the elderly and their families to avoid falling, as they recognize the importance of nursing in prevention work; consider the Systematization of Nursing Assistance (SAE) as a facilitating tool of nursing,