Lead, cadmium, nickel and other industrial metals used as part of paint varnishes have been reported to have adverse health implications. An evaluation study on some toxicological effects of occupational exposure to paint, among 25 occupationally exposed artisans and 25 students (control) of Ichi Technical College, Ichi Ekwusigo Local Government Area, Anambra State, Nigeria was carried out. Heavy metals were analysed by atomic absorption spectrophotometry and standard assay procedures were employed for biochemical parameters. The biochemical indices used include serum electrolytes urea, creatinine, alanine (ALT) and aspartate aminotransferases (AST), alkaline phosphatase (ALP), conjugated and total bilirubin. Others include blood lead, serum cadmium and nickel. Our results showed that occupational exposure of humans to paints increased the blood lead (39 +/- 4 microg/dL), serum cadmium (13 +/- 1 microg/dL) and nickel (63 +/- 1 microg/dL), when compared with non-paint factory workers (PFW) lead (17 +/- 4 microg/dL), serum cadmium (9 +/- microg/dL) and nickel (25 +/- 44 microg/dL), significantly at P < 0.05 lower values were observed for serum sodium (138.96 +/- 0.58 mmol/L), bicarbonate (26.88 +/- 0.39 mmol/L), urea (3.15 +/- 0.13 mmol/L) and creatinine (80.48 +/- 1.04 micromol/L) for paints factory workers when compared with non-paint factory workers, sodium (139.84 +/- 0.62 mmol/L), bicarbonate (26.20 +/- 0.22 mmol/L), urea (3.44 +/- 0.11 mmol/L) and creatinine (80.40 +/- 1.55 micromol/L); at P > 0.05. The activities of AST (10.36 +/- 0.58 micro/L), ALT(8.76 +/- 0.47 micro/L) and ALP (47.12 +/- 3.33 micro/L) in PFW were slightly elevated compared with non-PFW. Our result indicates that occupational exposure of humans to heavy metals in paints may have long term deleterious effects on liver and renal functions. In conclusion, it should be noted that occupational exposure to cadmium or lead among PFW, may compromise the liver and renal functions in man.

An enormous deficiency lag exists in the demand and supply of potable water in Umuahia, Abia State, Nigeria. The people have to pay lots of money to get potable water from water vendors, and those who cannot afford to pay patronize other unwholesome sources. Ossah River, one of the local drinking water sources, was studied to assess the heavy metal content and health risk assessment vis-a-vis its suitability for human consumption. Eight (8) heavy metals (Mn, Cu, Pb, Fe, Zn, Cd, Cr and Ni) were assessed between January and June 2018 in 3 stations, using atomic absorption spectrometer, and compared with Nigerian drinking water standards. Some of the heavy metals evaluated exceeded standards and warranted health risk assessment. Health risk assessment for all the stations indicated that there is no particularly dangerous single heavy metal, but their cumulative effect, indicated by the hazard index (HI). HI for all the stations highly exceeded threshold value (1). This calls for concern for both adults and children exposed to the water through ingestion. The heavy metal contamination observed was geogenic, exacerbated by anthropogenic activities.