Health care workers, nurses, and nursing students face a high risk of workplace aggression and violence. Potential adverse consequences oblige health care providers and educators to protect the safety of everyone in the health care setting. It is broadly agreed that health care personnel should receive education and training in the management of work-related aggression and violence. However, there are no training programs designed to meet the specific needs of nursing students. In the absence of Irish or international policies or guidelines, an evidence-based training program for first-year undergraduate nursing students was developed. Its focus was to enable nursing students to recognize potential problems and develop the skills necessary to appropriately handle situations that may arise during their clinical nursing practice. This article outlines the development and delivery of a training program for first-year nursing students, entitled Managing Challenging Situations in Practice.