Retinal hemorrhages were evident as early as 11 min after injection. It is suggested that this enzyme degraded selectively basement membrane components without affecting other proteins involved in the vitreous-retinal junction.

Purpose: To correlate the values of intraocular pressure (IOP) obtained by applanation tonometer (Haag-Streit, Bern, Switzerland) in patients with diabetes mellitus (with or without diabetic retinopathy), hypertension (with or without hypertensive diabetic retinopathy) and the normal population.Patients and Methods: Subjects participating in the Glaucoma Project (n = 924, 40 or more years old) were examined according to standard protocols including IOP measurement, fundoscopy, blood pressure and glucose determination. Patients were divided into seven groups: diabetic patients without diabetic retinopathy, hypertensive patients without hypertensive retinopathy, diabetic hypertensive patients without retinopathy, diabetic patients with diabetic retinopathy, hypertensive patients with hypertensive retinopathy, diabetic hypertensive patients with retinopathy and population-based control.Results: Applying the one-way ANOVA test to a normal distribution at 5% significance, it was observed that IOP values were higher in the groups of hypertensive patients without retinopathy (mean = 16.10), hypertensive patients with hypertensive retinopathy (mean = 16.33) and diabetic hypertensive patients with retinopathy (mean = 16.95) when compared with the other groups.Conclusion: The mean IOP value increases progressively with the evolution of systemic hypertensive disease and when it is associated with diabetes.

Achados oculares e fundoscópicos em pacientes com lupus eritematoso sistêmico apresentaram alteração fundoscópica relacionada ao LES. As principais lesões encontradas foram manchas algodonosas e estreitamento arteriolar (68,42%), seguidas de aumento da escavação (10,52%) e palidez do disco óptico (10,52%), lesão perivascular (5,26%) e alteração no epitélio pigmentar da retina (5,26%).Conclusão: Observou-se alta prevalência de alterações fundoscópicas relacionadas ao LES, demonstrando a importância de exames fundoscópicos regulares mesmo em pacientes lúpicos assintomáticos ou sem doenças associadas.

Lesão de superfície ocular em unidade de terapia intensiva: ensaio clinico auto-pareadoOcular surface injuries at an intensive care unit: a self-paired clinical trial Lesiones de la superfi cie ocular en unidad de cuidados intensivos: ensayo clínico autocontrolado

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