These results together indicate that MMP-2 activity can be promoted in keloid fibroblasts between collagen bundles in cooperation with TIMP-2 and MT1-MMP. This could contribute to remodelling of collagen bundle regions and invasion of fibroblasts into peripheral normal regions through promoted degradation of ECM.

This technique can be performed readily and is applicable to the reconstruction of relatively large defects and is also aesthetically excellent because of a postoperative suture line that is consistent with the topographic curve. This technique may be useful for medial canthal reconstruction.

Recent innovations in laser scanning technology provide a potentially useful technique for accurate three-dimensional documentation of the face. In this study, linear and area measurements of the facial contour and facial units have been recorded in a variety of chosen facial postures using surface laser scanning combined with three-dimensional lighting techniques on seven healthy volunteers and three patients with facial nerve paralysis. Three-dimensional surface measurement of the face was taken using a laser light scanner. Computer graphics lighting techniques were used to produce facial images constituted by highlights and shadows, which emboss facial contour and units. Then quantitative measurement of changes in facial angles and areas were made to analyze morphological changes of the face accompanying facial expression. Changes of angles and widths of the cheek and nasal units were found to be associated with dimensional changes imposed by the action of the underlying mimetic muscles. This system has potential value for both dynamic monitoring and evaluation of facial contour, units, and movement.

No abstract