Three lipid-oligonucleotides (ODN) carrying TEMPO were prepared and formed a micelle with a diameter of ca. 10 nm. The double strand ODN, lipid-polyT in DS, incorporating TEMPO near the core of the micelle showed the largest water-proton relaxivity, r 1 , value of 2.4 (25 MHz, 0.59 T) and 6.8 mM 21 s 21 (42 MHz, 1.0 T) per TEMPO.DNA derivatives carrying stable aminoxyls through various types of linkers have previously been prepared, revealing not only the conformation of various DNA strands but also their dynamics. 1 Such DNA double strands carrying organic spins could be expected to function as metal-free and large-size MRI agents, 2 taking advantage of the unique properties of the DNA strand, which binds to many water molecules in major and minor grooves for structural stabilization. 3 Recently, we reported that the double strand incorporating 5-uridine-TEMPO, UST, had relatively large water-proton relaxivity, r 1 , which is an indicative value for the contrast. 4 To increase the molecular size and further improve of the r 1 value, in this study DNA-micelles 5 carrying TEMPO, 2,2,6,6tetramethylpiperidine-N-oxyl, were prepared. The 15-mer of thymidine (polyT) and TEMPO-uridine (TDU) directly attached to the TEMPO radical without a linker, were selected as the base sequence and a spin source, respectively. We report the rotational correlation time, t R , and the relaxivities, r 1 , for their single-strand and double-strand micelles with complimentary strand (polyA), in addition to T 1 -weighted images in vitro (Fig. 1).The TDU monomer, was prepared by Suzuki coupling reaction; 5-iodo-29-deoxyuridine reacted with 4-borate TEMPO in the presence of tetrakis(triphenylphosphine)palladium(0). After pro-

A total of 1085 strains of Acinetobacter sp. obtained from 280 medical institutions in the Chugoku and Shikoku areas of Japan were investigated between 2011 and 2013. Among these strains, 20 (1.84 %) showing meropenem or imipenem resistance with a MIC of .4 mg ml 21 were detected. Of these 20 strains, the bla OXA-23 gene was detected in 17 strains isolated from the same institution. The PFGE patterns of the 17 strains were separated into two clusters, and multi-locus sequence typing showed the sequence types (STs) to be ST2 and ST246. This investigation demonstrated that A. baumannii ST2 of international clone II, which has rarely been isolated in Japan, has not yet spread nationwide.

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Synthesis and Properties of Tetrathiafulvalene Derivatives Containing Quinoid Structures: Novel Electron Donors of Organic Conductors. -Twofold Wittig-Horner reaction of the benzoquinone -cyclopentadiene adduct (I) with the benzodithiolephosphonate (II) gives after Retro-Diels-Alder reaction the new type of electron donors (III) which show reversible oxidation waves on cyclic voltammetry and form complexes with TCNQ and DDQ. -(SAITO, K.; SUGIURA, C.; TANIMOTO, E.; SAITO, K.; YAMASHITA, Y.; Heterocycles 38 (1994) 10, 2153-2158; Dep. Appl. Chem., Inst. Technol., Nagoya 466, Japan; EN)