For the neuropsychological impairment which takes place in HIV-1 infection, various classification systems, based on either neuropathological criteria, severity of the disorder or functional criteria, have been suggested in the literature. This study identifies the patterns of neurocognitive disorders in HIV-1 infection and investigates their stability at one-year follow-up. Two hundred and seventeen HIV-1-positive subjects in various stages of infection and 55 HIV-1-negative subjects were evaluated. Our results suggest that there is considerable diversity in the neuropsychological functioning of HIV patients but the patterns are relatively stable, functionally distinct, and differ with respect to the severity of the deficit. The overall pattern is consistent with existing neuropsychological knowledge on HIV infection. Comparison of the patterns identified in this study with other classification systems posed several problems, however, and these problems may have important implications for the theory and methodology of neuropsychological HIV research.

Prediction of MCI to dementia conversion can be improved by supplementing the neuropsychological tests with odor identification tests. A follow up study of hippocampus volume reduction, OI performance and cognitive functions deterioration will further increase prediction accuracy.

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Background. Previous studies carried out in different countries indicated that young adults experience higher levels of depressive and anxiety symptoms than older age groups during the COVID-19 pandemic. However, little is known about which epidemic-related difficulties and factors may contribute to these forms of emotional distress in various age groups. Purpose. The aim of the current study was to investigate: (i) differences in levels of depressive and generalized anxiety symptoms, as well as perceived difficulties related to pandemic across four age groups in the Polish population; (ii) which factors and difficulties related to pandemic are predictors of generalized anxiety and depressive symptoms in various age groups during the COVID-19 lockdown. Method. A total of 1115 participants (aged 18-85) took part in the study. The group was a representative sample of the Polish population in terms of sex, age, and place of residence. Participants completed online: The Patient Health Questionnaire-9, The Generalized Anxiety Disorder-7, Scale of Perceived Health and Life Risk of COVID-19, Social Support Sale, Scale of Epidemic-Related Difficulties. Results. Younger age groups (18-29 and 30-44) experienced higher levels of depressive and generalized anxiety symptoms than older adults (45-59 and 60-85 years). Difficulties in relationships and at home were amongst the strongest predictors of depressive and generalized anxiety symptoms in all age groups. Fear and uncertainty related to the spread of the virus were one of the most important predictors of emotional distress in all the groups apart from the adults between 18-29 years, whereas difficulties related to external restrictions were one of the most significant predictors of depressive and anxiety symptoms only in the youngest group. Conclusions. Our results indicate that the youngest adults and those experiencing difficulties in relationships among household members were the most vulnerable to depressive and generalized anxiety symptoms during the COVID-19 lockdown. Thus, it is important to plan preventive and therapeutic interventions to support these at-risk individuals in dealing with the challenges related to the COVID-19 pandemic.

Deficits in cognitive aspects of ToM are best explained by impairment of pragmatic competence and executive functions. In contrast, executive dysfunction does not affect the ability to understand the affective mental states of others. (PsycINFO Database Record