The effects of both ureas and amides on the native conformation of the four-chain human hemoglobin and the single-chain component of Glycera dibranchiuta hemoglobin were investigated by spectral and optical rotatory dispersion methods. Both techniques give similar transition profiles with essentially the same midpoints, S ,
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.