Background Dermatobia hominis (D. hominis) is a botfly that causes furuncular myiasis in several species of domestic and wild animals. However, reports of feline infestation by larvae of this dipteran are rare. Objective To report the natural occurrence of furuncular myiasis caused by D. hominis in five cats and the efficacy of topical fluralaner for its treatment. Animals Five adult mixed‐breed cats (four males, one female) were diagnosed and treated, all living in the state of Rio de Janeiro, Brazil. Results The cats were treated with topical fluralaner. After this treatment, the larvae were dead after 24 h in three cats and after 48 h in two. There was spontaneous expulsion of larvae in two cats, and it was necessary to perform manual expression for removal of dead larvae in the other three cats. Conclusions and clinical importance Dermatobia hominis can cause furuncular myiasis in cats, although this appears to be less common than in other animal species. Topical fluralaner proved to be effective in the treatment of this parasitic disease.

Fipronil (FIP) is an ectoparasiticide of the phenylpyrazole class, used in veterinary medicine in topical form. Supported by evidence of uncontrolled human exposure to FIP and environmental damage caused by commercially available formulations, its use by oral administration has become promising. The effectiveness of FIP against the flea Ctenocephalides felis felis and the tick Rhipicephalus sanguineus and its pharmacokinetics and main active metabolite, fipronil sulfone (SULF) were evaluated after single oral administration of tablets in three different doses (2, 4, and 6 mg/kg) in dogs. Through the plasma concentration curves, it was possible to observe that the FIP showed rapid absorption and metabolization and slow elimination. The values of Cmax (β = 0.7653) and AUC0‐t (β = 0.3209) did not increase proportionally with increasing dose. At 48 h after treatment, doses of 4 mg/kg (AUC0−t = 442.39 ± 137.35 µg/ml*h) and 6 mg/kg (AUC0−t = 421.32 ± 102.84 µg/ml*h) provided 100% and 99% efficacy against fleas, and 95% and 98% against ticks, respectively. The estimated EC90 of FIP +SULF was 1.30 µg/ml against C. felis felis and 2.16 µg/ml against R. sanguineus. The correlation between the FIP pharmacokinetic and efficacy data demonstrated its potential for oral administration in the form of tablets for the control of ectoparasites in dogs, as a safer alternative for animals, humans, and the environment, aligned with the One Health concept.

The aim of this study is to report the efficacy of nitenpyram against Cochiliomiyia hominivorax larvae in ocular myiasis of a naturally infested dog. A female Beagle with ocular myiasis was attended. After care and clinical examination, the involvement of the entire ocular and periocular region was found. The animal was treated orally with a dose of 4.7 mg/kg of nitenpyram together with analgesic medication. The expulsion and fall of live and dead larvae were evaluated by quantification every 15 minutes in the first hour and thereafter at 2, 3, 4, 6 and 18 hour intervals, followed by manual removal of the larvae. Overall effectiveness, larval expulsion rate and larvicidal effect of nitenpyram were determined. In all, there were 140 larvae in the lesion, of which 90 live and 46 dead larvae were expelled, while 4 dead larvae were mechanically removed, presenting 100% overall effectiveness, with larval expulsion activity of 97.1% and larvicidal efficacy of 35.7%. Based on the results obtained in this case, it can be concluded that nitenpyram has rapid and safe action against C. hominivorax larvae, making it a promising therapeutic alternative for the elimination of myiasis in the orbital cavity of dogs.

Purulent fibrous and necrotizing ileitis secondary to intussusception associated with infection by Giardia intestinalis and Cystoisospora felis in a cat-case report Ileítefibrino purulenta e necrosante secundária a intussuscepção associada a infecção por Giardia intestinalis e Cystoisospora felis em gato-relato de caso