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Retinal vasculitis represents a group of diseases characterized by inflammation affecting the retinal vasculature. It is an uncommon disorder that may occur as an isolated disease or more commonly in association with other ocular diseases or a variety of systemic diseases. With a wide variety of disease associations, a search for an underlying etiology should be undertaken based on a meticulous history, review of systems, and physical examination. The laboratory evaluation of patients with retinal vasculitis is an essential component of the work-up to facilitate detection of any underlying disease or to establish a limited differential diagnosis. The management of infectious causes of retinal vasculitis consists of antimicrobial therapy while noninfectious retinal vasculitis is managed with corticosteroids and/or immunosuppressive agents. Because retinal vasculitis is an uncommon disease, there are only a limited number of publications over the past year related to this topic.

Endophthalmitis in postoperative silicone oil-filled eyes is rare. The traditional management of these eyes is a return to the operating room for oil removal, instillation of intravitreal antibiotics, and reinjection of silicone oil. We describe 2 cases of endophthalmitis successfully treated with an office injection of intravitreal antibiotics. In both eyes, there was a prompt resolution of endophthalmitis with no apparent signs of retinal toxicity and with favorable visual outcomes. These are the first cases to be described of endophthalmitis in silicone oil-filled eyes successfully treated with intravitreal antibiotics alone.

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