Introduction Adolescence is characterized by the onset of a relatively specific set of socioemotional disorders (i.e., depression, generalized anxiety disorder, social anxiety disorder, and eating disorders) as well as body dysmorphia symptoms. Appearance‐related concerns are a central feature of these disorders. Emerging evidence in adults suggests that appearance‐related safety behaviors may play an instrumental role in the onset and maintenance of a number of disorders. To date, no work has examined appearance‐related safety behaviors during adolescence. The present study examined the extent to which appearance‐related safety behaviors may be associated with socioemotional and body dysmorphia symptoms during adolescence. Methods Adolescents between the ages of 13 and 17 years old (N = 387, Mage = 14.82 years, 31.3% identified as male, 47.0% identified as female, and 19.1% identified as nonbinary/third gender, 2.6% declined to report gender identity) completed measures assessing negative affect, anxiety‐relevant safety behavior use, cognitive reappraisal, expressive suppression, appearance‐related safety behaviors, body dysmorphia symptoms, and socioemotional symptoms. Structural Equation Modeling was used to test hypotheses. Results The results of this study suggest that appearance‐related safety behaviors evidenced associations with latent factors corresponding to affective (i.e., depression, generalized anxiety disorder, social anxiety), eating disorders, and body dysmorphia symptoms after controlling for previously established vulnerability factors. Conclusions These findings demonstrate that appearance‐related safety behaviors may evidence transdiagnostic associations with socioemotional symptoms and body dysmorphia symptoms during adolescence.