From the vantage point of northern Illinois, this article considers how the availability of organic, heirloom, and other specialty foods through a wider variety of grocery stores and online venues is affecting local food systems. Farmers concerned about these new forms of competition develop coping strategies to woo customers, but many of these strategies demand new skill sets and drain farmers’ time and resources away from the fields. How sustainable are local food systems when small‐scale farmers must be not only skilled producers, but marketing gurus, gregarious spokespeople, and public educators as well? More contextually grounded qualitative and mixed‐methods research is needed to help local food advocates and farmers understand and ease this entrepreneurial treadmill. [local food systems, direct market agriculture, small‐scale farmers, competition, United States]

Through ethnographic and historical analysis of the Negev region of Israel, this article examines competitive planting as a common tool in land conflicts. In a context of disputed land ownership, some Bedouin Arab residents plant crops in defiance of government policy. Government enforcers of land-use regulations destroy many of these crops and engage in counterinsurgent tree-planting. I suggest that planting is such a potent tactic because it draws on "environmental idioms" of agricultural labor, the rootedness of trees, and a fundamental Jewish-Arab opposition that have been central to the development of both Israeli and Palestinian nationalisms. For Bedouin Arabs, whose relationship to both nationalisms has long been contested, the multivalent symbolism of planting makes it a particularly promising tactic for asserting land claims. Further, I contend that these plantings demonstrate both the power of environmental idioms to structure land claims along ethnic lines and the creative potential of participants to challenge dominant environmental discourses by adding new connotations.

Cellular transdifferentiation changes mature cells from one phenotype into another by altering their gene expression patterns. Manipulating expression of transcription factors, proteins that bind to DNA promoter regions, regulates the levels of key developmental genes. Viral delivery of transcription factors can efficiently reprogram somatic cells, but this method possesses undesirable side effects, including mutations leading to oncogenesis. Using protein transduction domains (PTDs) fused to transcription factors to deliver exogenous transcription factors serves as an alternative strategy that avoids the issues associated with DNA integration into the host genome. However, lysosomal degradation and inefficient nuclear localization pose significant barriers when performing PTD-mediated reprogramming. Here, we investigate a novel PTD by placing a secretion signal sequence next to a cleavage inhibition sequence at the end of the target transcription factor–achaete scute homolog 1 (ASCL1), a powerful regulator of neurogenesis, resulting in superior stability and nuclear localization. A fusion protein consisting of the amino acid sequence of ASCL1 transcription factor with this novel PTD added can transdifferentiate cerebral cortex astrocytes into neurons. Additionally, we show that the synergistic action of certain small molecules improves the efficiency of the transdifferentiation process. This study serves as the first step toward developing a clinically relevant in vivo transdifferentiation strategy for converting astrocytes into neurons.

Why, with local food’s rising popularity, do small-scale farmers report declining sales? This study used a mix of survey and interview methods to examine the priorities and buying habits of food shoppers in one midsized, lower-income metro­politan area of the U.S. Midwest. The study focuses on individual consumers’ decision-making because it aims to be useful, in particular, to small-scale farmers and advocates of their participation in local and regional food systems. Among shoppers’ stated priorities, the survey found broad support for local food and relatively low competition be­tween price and local origin as purchasing priori­ties. However, findings also show an attitude-behavior gap, with only a limited increase in ten­dency among self-defined “local” shoppers to purchase from locally oriented venues. As explana­tion for this attitude-behavior gap, survey and interview data point to differential definitions of “local food” and situational barriers (primarily inconvenience and lack of variety) preventing shoppers from buying local food. One factor off­setting these barriers was past experience growing one’s own food. Study findings are used to identify particular avenues for intervention by farmers, eaters, and other food systems builders to broaden access to local food through adjustments to mar­keting strategies, better alignment of wholesale outlets’ practices with the priorities of farmers and eaters, and improved public education about the food system.