An immunohistochemistry panel of cytokeratin, vimentin, insulin-like growth factor II mRNA-binding protein 3 and glucose transporter 1 could provide superior information compared with haematoxylin and eosin staining alone in the diagnosis of cases of mesothelial proliferation in canine pericardium, but further validation is warranted.
PurposeTo evaluate the clinical outcome, possible complications, and recurrence rate of distichiasis in dogs treated with partial tarsal plate excision (PTPE) technique using a transconjunctival approach.MethodsRetrospective study including 17 client‐owned canine patients affected with distichiasis and presenting with associated clinical signs (ie, blepharospasm, epiphora, chronic keratoconjunctivitis, or corneal ulceration) that underwent surgical removal of the aberrant lashes using a PTPE technique between January 2018 and February 2019. Data collected included breed, age, sex, affected eyelid(s), number of distichia, and tear film breakup time (TBUT). Resected cilia‐bearing tarsoconjunctival strips were submitted for histopathological analysis.ResultsThirty eyes (52 eyelids) from 17 dogs were included in the study. The median age was 688 days (range 118‐4243 days). A successful outcome, defined as complete resolution of clinical signs attributable to the distichia, occurred in all eyes after a single procedure, with a mean follow‐up time of 239 days (range 69‐480 days). Appearance of new distichia occurred in 14/30 eyes (46.3%), and of these, three eyes needed a new PTPE procedure. Recurrence of the distichia only occurred in one eye (3.3%) which was asymptomatic. Following surgery, TBUT decreased below the normal value in 7/24 eyes (29.1%) although none developed clinical signs of qualitative tear film deficiency. Post‐operative complications included trichiasis and cicatricial entropion, which developed in two eyes (6.6%), and these were successfully managed with corrective eyelid surgery.ConclusionsPartial tarsal plate excision, using a transconjunctival approach, had an excellent clinical outcome with a low incidence of complications.
Case summary
A 14-year-old neutered female Burmese cat was referred for investigation of a
caudal oropharyngeal mass. CT showed a thin walled cyst-like structure
filling and expanding from the right tympanic bulla. Histopathology showed
fragments of mildly dysplastic squamous epithelium and aggregates of
keratin. These findings were considered consistent with a diagnosis of
cholesteatoma.
Relevance and novel information
To the best of our knowledge, this is the first reported case of a
cholesteatoma in a cat. Cholesteatoma should be considered a differential
diagnosis for cats presenting with a caudal oropharyngeal mass, a history of
chronic ear disease or a history of previous, surgically managed middle ear
disease. Advanced imaging and biopsies should be considered important in the
diagnosis of these lesions.
Complications arising from veterinary dental regional anaesthesia appear to be rare; however, it may be that they are under-reported. This case report highlights the risks involved and reviews the safest and most efficacious regional anaesthesia technique for the feline maxilla.
A 13-year-old male neutered British blue cat presented with uveitis, hyphema, and dyscoria in the right eye. Light microscopic examination revealed that the ciliary body, iris root, drainage angle, and adjacent choroid were infiltrated by sheets of large neoplastic mononuclear and multinucleate round to polygonal cells. Neoplastic cells stained immunopositive for CD18 and HLA-DR (MHC class II) and were immunonegative for CD3, CD79a, MUM-1, CD117 (c-Kit), and S100. These findings were consistent with a histiocytic sarcoma. The cat later developed multiple cutaneous masses composed of a similar neoplastic cell population to that seen in the eye. Eight months following enucleation, the cat developed respiratory distress and was euthanized. Postmortem examination revealed multiple pulmonary tumors associated with a pleural effusion.
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