No abstract

No abstract

No abstract

No abstract

This study analyzed the antimicrobial effects of compounds present in the roots and leaves of Citrus x limon (L.) Osbeck to help understand how this plant (1) ecologically modulates microbial defense in the rhizosphere and (2) protects against food-borne bacterial pathogens. Antimicrobial effects of C. limon collected from a farm in Foumban in Cameroon are reported against Salmonella typhi, Salmonella typhimurium, Salmonella enteritidis, Escherichia coli, Shigella f lexineri, and Saccharomyces cerevisiae. The study modeled synergistic antifungal effects of an essential oil from the roots of C. limon or E-caryophyllene when combined with the isolated compounds against S. cerevisiae. Twenty-four compounds were identified from the methanol extracts of the roots and leaves: 10 prenylated coumarins (1−10), six methoxylated flavones (11−16), two limonoids (18 and 19), a phenylalanine derivative (20), lupeol, stigmasterol, sitosterol, and sitosterol-3-O-β-D-glucoside. Major compound 16, atalantoflavone, was esterified using lauric acid to yield the undescribed 5,4′-dilaureate atalantoflavone (16a). The essential oil from the roots contained methyl esters of hexadecanoic acid (39%) and 9-octadecenoic acid (9.3%) and sesquiterpenes β-bisabolene (10.1%) and α-santalene (8.0%).