Systematic inflammation, enhanced oxidative stress, and endothelial dysfunction are important for evolution and progression of renal damage, and they cause an increase in red cell distribution width (RDW). Familial Mediterranean fever (FMF) patients who are in the attack-free period and its relation with albuminuria and performance on assessment of microalbuminuria. One hundred and seventy-seven patients who had been diagnosed in accordance with Tel-hoshmer criteria and were in the attack-free period, and 143 age- and sex-matched healthy individuals were enrolled in our study. RDW values of FMF patients were higher compared with those of the controls (13.85 ± 1.07 and 13.15 ± 0.91, respectively; p < 0.0001). RDW values of FMF patients with microalbuminuria were higher compared with those of FMF patients with normoalbuminuria and the control group (p = 0.002 and p < 0.0001, respectively). RDW values of FMF patients with normoalbuminuria were higher compared with those of the control group (p < 0.0001). We have showed RDW levels are positively correlated with albuminuria (r = 0.185, p = 0.014). When assessing microalbuminuria with RDW in the patients, a cutoff value of 13.85 with sensitivity of 60%, specificity of 62%, and p = 0.002 (area under curve: 0.651, 95% confidence interval 0.563-0.738), was observed according to receiver-operating characteristic curve analysis. Among the various variables associated with albuminuria in multivariate logistic regression analyses, RDW remained an independent predictor of albuminuria (95% confidence interval 0.479-0.942, p = 0.021). RDW may be associated with albuminuria in FMF patients and it can be a predictor of microalbuminuria.
Hydatid cyst (CH), which is quite common in the world, mostly transmitted by dog faeces, is a parasitic disease caused by Echinococcus granulosus. CH often infects the liver and lungs. During the clinical course, renal involvement is rarely seen. In this article; due to liver hydatid disease, mezengioproliferatif glomerulonephritis case is presented. KEY WORDS: Echinococcus granulosus, Hydatid cyst, Mesangioproliferative glomerulonephritis ÖZKist hidatik (KH) dünyada oldukça yaygın olup çoğunlukla köpek dışkısı yoluyla insana bulaşan Echinococcus granulosus'un neden olduğu paraziter bir hastalıktır. KH sıklıkla karaciğer ve akciğere yerleşmektedir. Klinik seyri sırasında primer böbrek tutulumu nadiren görülür. Bu yazıda karaciğer kist hidatiğine sekonder, sıra dışı renal bir tutulum olan mezengioproliferatif glomerülonefrit olgusu sunulmuştur.
Lupus nephritis is an inflammation of the kidney caused by systemic lupus erythematosus (SLE). Lupus nephritis is a frequent complication of SLE that increases mortality and morbidity. Minimal glomerular lesions, mesangial proliferative, focal proliferative, membranous and diffuse glomerulonephritis can be seen in renal biopsies of patients with lupus nephritis. It has been reported that non-lupus nephritis can also rarely occur in SLE. While non-lupus nephritis cases usually manifest as focal segmental glomerulosclerosis, they have been seen rarely as IgA nephropathy. In this paper, we have represented a SLE case with IgA nephropathy on renal biopsy
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