Background: Different non-motor neurological complaints are reported among the Parkinson’s disease patients. Objective: The purpose of the present study was to see the non-motor neurological complaints of Parkinson’s disease patients. Methodology: This cross-sectional study was carried out in the in-patient and out-patient Department of Medicine and Neurology of Sir Salimullah Medical College and Mitford Hospital, Dhaka from July 2012 to December 2013 for a period of one and half year. All patients with Parkinson’s disease who were admitted under department of Medicine and Neurology and also who visited out-patient department of Medicine and Neurology of Sir Salimullah Medical College and Mitford Hospital, Dhaka were included as study population. Patients who were diagnosed according to Brain Bank clinical criteria for diagnosis of Parkinson’s disease were included in this study. The non-motor neurological complaints were recorded. Result: This study was conducted in Sir Salimullah Medical College and Mitford Hospital with a view to see the non-motor neurological complaints of Parkinson’s disease. The mean age was found 69.15±10.08 years. Most of the patients had a combination of non-motor symptoms and among them more than two third (66.7%) of the patients had cognitive impairment; furthermore more than half (53.8%) of the patients had sleep disturbance. One fourth (25.0%) of patients had sensory, sleep and cognitive disorder; however, 9(22.5%) patients had sleep and cognitive disorder. Conclusion: In conclusion majority Parkinson’s disease patients are suffering from cognitive impairment followed by sleep disturbances. Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 123-126

Background: Depressive illness is present among Parkinson’s disease (PD) patients. Objective: The purpose of the present study was to see the influencing factors of development of depressive illness among Parkinson’s disease patients. Methodology: This comparative cross-sectional study was carried out in the Department of Neurology and Department of Psychiatry at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2009 to June 2011 for a period of two (2) years. Parkinson’s disease patients who were attended at the movement disorder clinic and general OPD of Department of Neurology and in-patient department of Neurology at BSMMU, Dhaka were selected as study population. Patients with Parkinson’s plus syndrome, with dementia or other causes of parkinsonism like vascular or drug induced parkinsonism were excluded from this study. Data were collected by filling structured clinical questionnaire, then filling up of ‘structured clinical interview for DSM-IV Axis I disorders’ (SCID-CV) and self-reported ‘Depression scale` questionnaire. Parkinson disease was diagnosed by neurologist by the presence of two or more of the four cardinal criteria namely tremor, rigidity, bradykinesia and postural instability. Then patients were screened for depression by a psychiatrist of Department of Psychiatry at BSMMU, Dhaka. Result: A total of 100 Parkinson’s disease patients were interviewed and 80 patients ultimately participated in the study. The mean age of total Parkinson’s disease patients was 57.71±12.36 years ranging from 35 to 82 years with highest percentage (35%) had age group 65 years or above, 28.7% in 55 to 64 years, 22.5% in 45 to 54 years and lowest percentage (13.8%) in age group less than 45 years. Among 80 Parkinson’s disease patients, depression was present in 34 (42%) patients and was absent in 46 (58%) patients. Diabetes mellitus (p=0.125), hypertension (p=0.097), hypothyroidism (p=1.000), other illness (p=0.595), family history of PD (p=0.758) and levodopa use (p=0.661) were not significantly associated with the development of depressive illness in Parkinson’s disease. Conclusion: Diabetes mellitus (DM), hypertension (HTN), hypothyroidism, other illness, family history of PD and levodopa use do not significantly influence in the development of depressive illness among the Parkinson’s disease. Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 106-110

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Background: Parkinson’s disease occurs in different socio-demographic characteristic people. Objective: The Purpose of the present study was to see the socio-demographic characteristics of Parkinson’s disease patients attended at a tertiary care hospital in Dhaka city. Methodology: This cross-sectional study was carried out in the in-patient and out-patient Department of Medicine and Neurology of Sir Salimullah Medical College and Mitford Hospital, Dhaka from July 2012 to December 2013 for a period of one and half year. All patients with Parkinson’s disease who were admitted under department of Medicine and Neurology and also who visited out-patient department of Medicine and Neurology of Sir Salimullah Medical College and Mitford Hospital, Dhaka were taken as study population. Patients who were diagnosed as Parkinson’s disease according to Brain Bank clinical criteria for diagnosis of Parkinson’s disease were included in this study. The demographic and socio-economic characteristics were recorded in a semi-structured questionnaire. Result: A total number of 40 Parkinson’s patients were recruited for this study. The mean age was 69.15±10.08 years. The male female ratio was found 1.22:1. The majority patients were businessman which was 13(32.5%) cases. The majority of 15(37.5%) patients came from rural area. However, 12(30.0%) patients were in primary level. Furthermore, 21(52.5%) patients came from lower class. Conclusion: In conclusion elder male rural dwellers are mostly suffering from Parkinson’s disease Journal of Current and Advance Medical Research 2019;6(2):106-110