No abstract

No abstract

Introduction: The number of TB cases in Indonesia was increasing and it is estimated that one in five is extrapulmonary TB, is believed that there is a high mortality rate for extrapulmonary TB. Aim: To assess difference in survival rates of HIV patients with pulmonary TB and extra pulmonary TB. Results: Based on Fisher's Exact test, it was found that there was no statistical difference survival rates of HIV patients with pulmonary TB and extra-pulmonary TB at H. Adam Malik Hospital in 2015-2018 (p=0.303). The mean survival of HIV patients with extrapulmonary TB was 4.3; and pulmonary TB patients was 3.5. Overall mean survival is 4.5 years. It was concluded that HIV patients with pulmonary TB was 1.21 times more likely to die than HIV patients with extrapulmonary TB (HR: 1.21; 95% CI 0.76-1.92). Conclusion: HIV patients with pulmonary TB had a lower survival rate than HIV patients with extrapulmonary TB but it was not statistically significant. The 50% survival rate for HIV patients with extrapulmonary TB is 4.3 years and for pulmonary TB is 3.5 years Keywords: HIV, co-infection, pulmonary TB, extrapulmonary TB, survival rates

No abstract

Background: The lungs are one of the primary target organs for HIV disease and a major source of morbidity and mortality, among others, caused by Pneumocystis carinii pneumonia (PCP) or recurrent bacterial pneumonia. In developing countries, the incidence of PCP infection has soared, with high mortality rates ranging from 20% to 80%. The increase in serum LDH plays an important role in determining the severity of the disease. This study aims to determine the role of LDH examination as a diagnostic tool for PCP and Arterial Blood Gases (ABG) in HIV and AIDS patients. Method: This research is an analytical study using an observational diagnostic test design, conducted from November 2020-January 2021 at the HIV Treatment Room at H. Adam Malik Hospital, Medan with 158 subjects. We calculate the value of sensitivity, specificity, positive predictive value, and negative predictive value. Results: 75.3% of the total sample was male, with the highest age group being 30-39 years old (46.2%) 126 samples (79.7%) had CD4 levels 200 cells/mm3, 98 samples (62%) had LDH levels > 500 U/L. In this study, 113 samples (71.5%) fell into the ABG criteria [PaO2] <70 mmHg). LDH has superior sensitivity and specificity value compared to ABG examination. In this case PaO2 or A-A DO2 in diagnosing PCP in HIV-AIDS patients. Conclusion: LDH examination combined with clinical and radiological examinations has good sensitivity and specificity in the diagnosis of PCP. Keywords: HIV, AIDS, Lactate dehydrogenase, PCP.