Aims and objectives:To synthesise evidence regarding vaccination intention, identify factors contributing to vaccine hesitancy among healthcare professionals and the general populations globally. Background:As COVID-19 vaccine becomes available worldwide, attention is being directed to community vaccine uptake, to achieve population-wide immunity. A number of factors have been reported to influence vaccine intention. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a systematic search of COVID-19 vaccination intention related literature published on or before 31 December 2020 from seven databases was undertaken.Results: Thirty articles were included in this systematic review. Overall COVID-19 vaccination intention during the first year of the pandemic ranged from 27.7% to 93.3%. Findings highlighted that socio-demographic differences, perceptions of risk and susceptibility to COVID-19 and vaccine attributes influenced vaccination intention. Healthcare professionals particularly, nurses have higher vaccine hesitancy reportedly due to concerns regarding vaccine safety and efficacy and mistrust of health authorities. Negative information about COVID-19 vaccines in the social media and low confidence in the health system were associated with lower acceptability among the community. Interestingly, cumulative increase in COVID-19 caseloads of countries over time was not associated with vaccination intention. Conclusions:The significant variability in vaccine intention rates worldwide would hamper efforts to achieve immunity against COVID-19. Nurses' concerns about vaccine safety and efficacy need to be addressed to increase vaccine acceptance and maximise their influence on vaccination decision in the community. As misinformation through social media negatively impacts vaccination uptake, authoritative and reliable information on vaccine attributes, disease risks and vaccination benefits are needed.

Adolescence is a critical phase in which physical, psychological, and intellectual challenges occur. This study assesses the prevalence and correlates of depression and anxiety among a national sample of adolescents. A cross-sectional correlational design using depression, anxiety, and stress scale was used. Our data revealed that 49.1% and 78.2% of Jordanian adolescents had severe depressive symptoms and anxiety, respectively. Depression and anxiety had a significant positive correlation with gender and age and a negative relationship with monthly income and fathers’ and mothers’ educational levels. Binary logistic regression revealed that the whole model for depression had a coefficient of determination X2: (4, N 1,344), R2 (.149); p < .005, whereas the overall model for anxiety showed a coefficient of determination X2: (4, N 1,344), R2 (.091); p < .005. This study indicates that depression and anxiety are highly prevalent among Jordanian adolescents. Thus, prioritizing funds for mental health services is paramount.