One-carbon homologation functionalization in organic synthesis is quite challenging and difficult task in terms of atom economy, ease of reaction, selectivity and number of steps involved. Due to the reactivity...

Inflammation is associated with many different class of diseases and NSAIDs (non-steroidal anti-inflammatory drugs) are mostly preferred for long-term use. Although it is safe to use but some serious side...

Oleogels are semi‐solid, thermo‐reversible and viscoelastic self‐assembled 3‐D networking structures in which edible oils are immobilized through physical interactions with oleogelators. Nowadays, oleogels have attracted the attention of researchers for its wide applications in pharmaceuticals, cosmetics and food industries. Therefore, we have prepared a new oleogel formulation for topical and transdermal applications of antimicrobial and antiseptic agent metronidazole with enhanced properties. Aminopyridinyl tricosanamide fatty acid amide oleogelator self‐assembled in edible oils, form stable/thermoreversible gel with good shear thinning and pseudoplasticity. Such oleogels may be excellent drug delivery vehicles for topical/transdermal applications due to their shear thinning and pseudoplastic behaviour. In addition, the pH of these gels fall in the range of skin pH which bodes well for potential applications on skin. These gels show a slow and controlled release of the drug in both acidic and slightly basic buffers, indicating long‐term antibacterial activity associated with such drug loaded oleogels.

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